Pulmonary function and respiratory muscle strength at hospital discharge in patients with COVID-19 after admission to the Intensive Care Unit
DOI:
https://doi.org/10.1590/1809-2950/21020629022022PTKeywords:
COVID-19, Respiratory Function Tests, Respiratory Muscles, Critical CareAbstract
The aim of this study was to describe pulmonary function and respiratory muscle strength (RMS) at hospital discharge of patients with severe COVID-19 cases and correlate with peripheral muscle strength, time on mechanical ventilation (MV) and hospital stay and use of medications.This is a cross-sectional study including patients who were admitted to the ICU for COVID-19. Theassessment at hospital discharge included the following variables: RMS, pulmonary function, and peripheral muscle strength [Medical Research Council score and handgrip dynamometry]. Twenty-five patients were included, with a mean age of 48.7±12.3 years. It was observed that 72% of patients had restrictive ventilatory disorder, in addition to reduced RMS [maximum inspiratory pressure (MIP) of 74% and maximum expiratory pressure (MEP) of 78% out of the predicted value]. RMS (MIP and MEP, respectively) correlated negatively with time on MV (r=-0.599, p=0.002; r=-0.523, p=0.007) and hospital stay (r=-0.542, p=0.005; r=-0.502, p=0.01), and positively with FVC (r=0.825, p=0.000; r=0.778, p=0.000), FEV1 (r=0.821, p=0.000; r=0.801, p=0.000), PEF (r=0.775, p=0.000; r=0.775, p=0.000) and handgrip strength (r=0.656, p=0.000; r=0.589, p=0.002).We conclude that patients with severe COVID-19 cases presented, at the time of hospital discharge, reduced RMS and changes in lung function, and a negative correlation between RMS and time on IMV and hospital stay, and a positive correlation with lung function and hand grip strength.
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