Oral delivery system for peptides and proteins: I. Approaches to improve oral bioavailability

Authors

  • Catarina Silva Universidade de Coimbra; Faculdade de Farmácia; Laboratório de Tecnologia Farmacêutica
  • António Ribeiro Instituto Superior de Ciências da Saúde do Norte; Laboratório de Tecnologia Farmacêutica
  • Domingos Ferreira Universidade do Porto; Faculdade de Farmácia; Laboratório de Tecnologia Farmacêutica
  • Francisco Veiga Universidade de Coimbra; Faculdade de Farmácia; Laboratório de Tecnologia Farmacêutica

DOI:

https://doi.org/10.1590/S1516-93322002000200002

Keywords:

Absorption enhancer, Formulation, Microencapsulation, Peptide drugs, Protease inhibitors

Abstract

There are hundreds of peptides and proteins clinically relevant. The difficulties associated with their oral administration have been responsible for the major efforts in developing ways to improve oral bioavailability. Both these subjects are described in this review. The potentiality of microencapsulation presents this technique as a privileged approach for the oral delivery of peptide and protein drugs.

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Published

2002-06-01

Issue

Vol. 38 No. 2 (2002)

Section

Reviews

How to Cite

Oral delivery system for peptides and proteins: I. Approaches to improve oral bioavailability. (2002). Revista Brasileira De Ciências Farmacêuticas, 38(2), 125-140. https://doi.org/10.1590/S1516-93322002000200002