Biocompatibility assessment of silicone gel breast implants sterilized by dry-heat and by ethylene oxide

Authors

  • Janice Campos de Azevedo Universidade de São Paulo; Faculdade de Ciências Farmacêuticas; Departamento de Farmácia
  • Áurea Silveira Cruz Instituto Adolfo Lutz
  • Terezinha de Jesus Andreoli Pinto Universidade de São Paulo; Faculdade de Ciências Farmacêuticas; Departamento de Farmácia

DOI:

https://doi.org/10.1590/S1516-93322006000200011

Keywords:

Breast implants, Silicone, Biocompatibility, Sterilization, Neutral red uptake, Ethylene oxide, Dry-heat

Abstract

Silicone breast implants have been widely used for mammary augmentation and reconstruction surgery. Biological safety of these implants can be altered by sterilization methods. This study consisted of the biocompatibility assessment of smooth and textured silicone gel breast implants sterilized by dry-heat and ethylene oxide through cell viability, employing neutral red uptake method. The NCTC clone 929 cell were employed and the results showed no cytotoxicity of implants after both sterilization processes.

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Published

2006-06-01

Issue

Vol. 42 No. 2 (2006)

Section

Original Papers

How to Cite

Biocompatibility assessment of silicone gel breast implants sterilized by dry-heat and by ethylene oxide. (2006). Revista Brasileira De Ciências Farmacêuticas, 42(2), 259-263. https://doi.org/10.1590/S1516-93322006000200011