Influence of the alkali metal cation on the fragmentation of monensin in ESI-MS/MS

Authors

  • Norberto Peporine Lopes Universidade de São Paulo; Faculdade de Ciências Farmacêuticas de Ribeirão Preto; Departamento de Física e Química
  • Filipe Alexandre Almeida-Paz Universidade de Aveiro; Departamento de Química; Centro de Investigações em Materiais Cerâmicos e Compósitos
  • Paul Jonathan Gates University of Bristol; School of Chemistry

DOI:

https://doi.org/10.1590/S1516-93322006000300006

Keywords:

Polyether ionophore, Monensin, Alkali metal complex, Electrospray tandem mass spectrometry

Abstract

The MS/MS fragmentation of the alkali metal complexes of monensin A are studied. The increase in alkali metal ionic radii decreases the ability of the Grob-Wharton fragmentation mechanism to occur and reduces the overall degree of fragmentation. Conversely, the electronegativity of the metal cation is related to the number of fragment ions observed.

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Published

2006-09-01

Issue

Vol. 42 No. 3 (2006)

Section

Original Papers

How to Cite

Influence of the alkali metal cation on the fragmentation of monensin in ESI-MS/MS. (2006). Revista Brasileira De Ciências Farmacêuticas, 42(3), 363-367. https://doi.org/10.1590/S1516-93322006000300006