Evaluation of the production of nitric oxide in mice, submitted to aerobic and anaerobic exercises

Authors

  • Vanessa Guimarães de Freitas Cruvelo D'Ávila Universidade Federal de Goiás; Instituto de Ciências Biológicas; Departamento de Bioquímica e Biologia Molecular
  • Nozelmar Borges de Sousa Júnior Universidade Salgado de Oliveira; Departamento de Desporto e Reabilitação
  • Fábio Borges de Sousa Universidade Federal de Goiás; Instituto de Ciências Biológicas; Departamento de Ciências Fisiológicas
  • Lídia Andreu Guillo Universidade Federal de Goiás; Instituto de Ciências Biológicas; Departamento de Bioquímica e Biologia Molecular

DOI:

https://doi.org/10.1590/S1516-93322008000400023

Keywords:

Sodium nitrate, Griess Reaction, Physical exercises^i2^sexperimental st, Arterial hypertension

Abstract

Nitric Oxide (NO) exerts important influences in several physiological processes. In this work we evaluated the production of sanguine NO in Wistar rats, submitted to the acute aerobic and anaerobic exercises. The formation of nitric oxide was verified through the dosage of the end products of oxidation of the metabolism of nitric oxide (nitrates). For this we used the colorimetric Griess method. We verified the existence of a significant difference (p = 0.000261) in the production of NO among the accomplishment of the aerobic swimming and the anaerobic, where the aerobic was shown more efficient in the promotion of higher levels. The acute aerobic exercise with duration of at least 10 minutes was shown more effective in the requirement production of NO in relation to the 5 minutes exercise. The positive relationship observed between the aerobic exercise and the formation of NO can help to explain the beneficial effects of the exercise in the cardiovascular health. We know that the practice of aerobic exercise and your duration increases the biodisponibility of NO, which is an important physiologic regulator of the blood pressure.

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Published

2008-12-01

Issue

Section

Original Papers

How to Cite

Evaluation of the production of nitric oxide in mice, submitted to aerobic and anaerobic exercises. (2008). Revista Brasileira De Ciências Farmacêuticas, 44(4), 755-761. https://doi.org/10.1590/S1516-93322008000400023