Antibacterial activity of Apocynaceae extracts and MIC of Tabernaemontana angulata stem organic extract

Authors

  • Ivana Barbosa Suffredini Universidade Paulista; Centro de Pesquisas Oncológicas; Laboratório de Extração
  • Elfriede Marianne Bacchi Universidade de São Paulo; Faculdade de Ciências Farmacêuticas; Departamento de Farmácia
  • Telma Mary Kaneko Sakuda Universidade de São Paulo; Faculdade de Ciências Farmacêuticas; Departamento de Farmácia
  • Mitsuko Taba Ohara Universidade de São Paulo; Faculdade de Ciências Farmacêuticas; Departamento de Farmácia
  • Riad Naim Younes Universidade Paulista; Centro de Pesquisas Oncológicas; Laboratório de Extração
  • Antonio Drauzio Varella Universidade Paulista; Centro de Pesquisas Oncológicas; Laboratório de Extração

DOI:

https://doi.org/10.1590/S1516-93322002000100009

Keywords:

Apocynaceae, Tabernaemontana angulata, Antimicrobiral activity, Amazon rain forest, Minimal Inhibitory Concentration (MIC)

Abstract

Thirty-eight aqueous and organic extracts obtained from 11 Amazonian Apocynaceae species were submitted to an antimicrobial dilution in broth media screening for Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans, performed on microtiter plates. The organic extract obtained from the stem of Tabernaemontana angulata presented activity against Gram positive Staphylococcus aureus. The minimal inhibitory concentration of the organic crude extract was 2.50-1.25 mg/mL. Cloramphenicol was used as standard. Alkaloids and triterpenes were found in the active organic extract.

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Published

2002-03-01

Issue

Vol. 38 No. 1 (2002)

Section

Original Papers

How to Cite

Antibacterial activity of Apocynaceae extracts and MIC of Tabernaemontana angulata stem organic extract. (2002). Revista Brasileira De Ciências Farmacêuticas, 38(1), 89-94. https://doi.org/10.1590/S1516-93322002000100009