Influence of using fluoxetine on run-time in treadmill in rats un trained
DOI:
https://doi.org/10.1590/S1807-55092012000300003Keywords:
Fluoxetin, Nervous system, ExhaustionAbstract
Works of different authors have been shown that an increase in the concentration of serotonin (5-HT) in the brain during intense and long-term physical exercise, is directly associated with a harm in the function of the Central Nervous System (CNS), with corresponding development of the fatigue and consequence decrease of the performance. In the present work, 10 rats Wistar were submitted to run-sessions until the exhaustion in treadmill. The experimental protocols were splited in 4 phases: Phase 1: evaluation of the range run-time of the animals until the physical exhaustion. Phase 2: evaluation of the range run-time of the animals until the physical exhaustion on treatment with fluoxetine. Phase 3: washout seven days. Phase 4 washout 14 days. The present study suggest that chronic administration of fluoxetine increase substantially the run-time until the physical exhaustion in rats submitted to exercises in treadmill.Downloads
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Published
2012-09-01
Issue
Section
Biodinâmica
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Todo o conteúdo da revista, exceto onde está identificado, está licenciado sob uma Licença Creative Commons (CC-BY)
How to Cite
Cuquetto, D. C., Mill, J. G., & Amaral, F. T. do. (2012). Influence of using fluoxetine on run-time in treadmill in rats un trained. Brazilian Journal of Physical Education and Sport, 26(3), 375-381. https://doi.org/10.1590/S1807-55092012000300003