Comparison of spinal inhibitions between parkisonian and helathy individuals

Authors

  • Carla Silva-Batista Universidade de São Paulo; Escola de Educação Física e Esporte
  • Carlos Ugrinowitsch Universidade de São Paulo; Escola de Educação Física e Esporte
  • Luana Daniela de Souza Yoshida Universidade de São Paulo; Escola de Educação Física e Esporte
  • André Luiz Felix Rodacki Universidade Federal do Paraná
  • Valmor Alberto Augusto Tricoli Universidade de São Paulo; Escola de Educação Física e Esporte
  • Marco Tulio de Mello Universidade Federal do Estado de São Paulo; Centro de Estudos de Psicobiologia do Exercício
  • Maria Elisa Pimentel Piemonte Universidade de São Paulo; Faculdade de Medicina
  • Eugenia Casella Tavares de Mattos Universidade Federal do Paraná

DOI:

https://doi.org/10.1590/S1807-55092013000200003

Keywords:

H-reflex, Spinal cord, Presynaptic inhibition, Dissinaptic reciprocal inhibition, Parkinson's Disease

Abstract

The purposes of the present study were to compare presynaptic inhibition (PI) and disynaptic reciprocal inhibition (DRI) levels between parkinsonians and healthy individuals and to verify the correlation of such inhibitions with muscle rigidity and clinical severity (assessed by the Unified Parkinson Disease Rating Scale). We evaluated 11 parkinsonians in stages 2 and 3 of the disease and 13 healthy individuals matched for age. The PI was significant lower in parkinsonians (31.6%) than in healthy individuals (67.1%) (p = 0.02). The DRI did not differ between parkinsonians (26.9%) and healthy individuals (27.6%) (p = 0.91). Furthermore, no significant correlation was observed between PI with muscle rigidity and clinical severity (p >; 0.05). Therefore, inhibitory mechanisms do not fully explain the cause of muscle rigidity and clinical severity of parkinsonians. Changes between the activation of agonist and antagonist muscles seem to be caused by abnormal supraspinal influence on spinal mechanisms.

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Published

2013-06-01

Issue

Vol. 27 No. 2 (2013)

Section

Biodinâmica

License

Todo o conteúdo da revista, exceto onde está identificado, está licenciado sob uma Licença Creative Commons (CC-BY)

How to Cite

Silva-Batista, C., Ugrinowitsch, C., Yoshida, L. D. de S., Rodacki, A. L. F., Tricoli, V. A. A., Mello, M. T. de, Piemonte, M. E. P., & Mattos, E. C. T. de. (2013). Comparison of spinal inhibitions between parkisonian and helathy individuals. Brazilian Journal of Physical Education and Sport, 27(2), 187-197. https://doi.org/10.1590/S1807-55092013000200003