Effect of physical training frequency on obesity and dyslipidemia prevention in normo and hypercholesterolemic rats

Abstract

Studies have shown a significant hypocholesterolemic effect of continuous exercise, however the effects of physical training made two times a week has been negligible. Therefore, the present study was developed to observe if different frequencies of exercise can promote adaptations in the lipidic metabolism of normo or hypercholesterolemic rats. Forty eight adults male Wistar rats were divided into six groups (n = 8): 1- Normocaloric diet: Sedentary (SP), Weekend Training (TP2), Continuous Training (TP5); 2- Hypercholesterolemic diet: Sedentary (SH); Weekend Training (TH2) and Continuous Training (TH5). The rats of the trained groups were submitted to the aerobic chronic moderate exercise (swimming), either five or two times a week on consecutive days during eight weeks. The present study show that in animals fed with hypercholesterolemic diet both exercise training regimes were important for reduction of body weight, central body fat (EPI and RET), lipogenese rate (EPI) and lipid profile modifications. However it is important to point out that the training accomplished five times a week was more effective in dyslipidemia and obesity control.