Visceral leishmaniasis and genetic susceptibility

Authors

  • Amanda Farage Frade Universidade de São Paulo. Faculdade de Medicina. Instituto do Coração. Laboratório de Alergia e Imunologia

DOI:

https://doi.org/10.7594/revbio.6b.05

Keywords:

Visceral leishmaniasis, genetic polymorphism, candidate genes, immunogenetic

Abstract

Visceral leishmaniasis is a serious infectious disease caused by an obligate intracellular protozoan of the genus Leishmania. The disease encompasses a wide spectrum of clinical manifestations, which can range from asymptomatic cases, to the classical form of the disease characterized by hepatosplenomegaly, fever and wasting, and even the more severe bleeding that can progress to death. Some factors can alter the severity of clinical manifestations, among them the genetic predisposition. Through research of genetic polymorphism it is possible to evaluate which genes may be related to susceptibility to infection and predisposition to the most severe forms of the disease

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Published

2018-04-23

Issue

Vol. 6 No. 2 (2011): Especial Parasitologia

Section

Revisão

License

We ensure that our journal does not retain any copyright and that these are exclusive of the author(s) of the text. In that sense, we intend to break any restrictions to the published material and to achieve more intensely our goal of communicating science.

How to Cite

Frade, A. F. (2018). Visceral leishmaniasis and genetic susceptibility. Revista Da Biologia, 6(2), 22-25. https://doi.org/10.7594/revbio.6b.05