A case o f basophil leukemia in a dog and its differentiation from a case of disseminated malignant mastocytoma

Abstract

Two cases of malignant disturbances on the production of basophils and mast cells were reported in dogs. The former was characterized by the presence of intensive basophilia with basophils of immature aspects and myeloid metaplasia foci within liver, spleen and lymph nodes in wich predominated basophils with the same aspects of the circulating ones. In the second case mast cells were predominant in the lymph nodes and metastatic foci associated with a slight increase in normal basophils and mast cells in the peripheral blood. The basophils in the first case and the mast cells in the second were differentiated by morphological and hystochemical methods.