Newcastle disease. II. A comparative study among different administration routes of B1, vaccine strain

Abstract

The influence of different methods of application of vaccines prepared with B₁ strain of Newcastle virus were studied in young birds obtained from immune matrixes. Their response was evaluated both by haemagglutination inhibition test (HI) and by the protection against a challenge test. Young birds, 14 days old, were primary vaccinated through aerosol, eye drop instillation or oral routes. Results showed that the aerosol method induced the most effective response on HI test (P<0,05). No differences were found between the eye drop instillation and the aerosol methods concerning protection against the challenge test. Further it was also observed that maternally derived antibodies declined quickly after birth being not detected in animals between 14 and 21 days old.