Secondary hypogammaglobilinemia after use of carbamazepine: case report and review
DOI:
https://doi.org/10.1590/S0041-87812001000600006Keywords:
Epilepsy, Immunodeficiency, Carbamazepine, Immunoglobulin, Anticonvulsant therapyAbstract
Immunologic disorders related to anticonvulsant therapy have been described in the last three decades, including cellular and humoral alterations that result in recurrent infections; however, the physiopathologic mechanisms are not completely understood. This report describes a patient with complex partial epilepsy and hypogammaglobulinemia while in treatment with carbamazepine, with significant improvement in clinical signs and laboratory tests after substitution to sodium valproate. The authors stress the importance of clinical and laboratory evaluation of patients in continuous anticonvulsant therapy, including immunoglobulins levels and peripheral blood evaluations.Downloads
Published
2001-12-01
Issue
Section
Review
How to Cite
Castro, A. P. B. M., Redmershi, M. das G., Pastorino, A. C., Paz, J. A. da, Fomin, A. B. F., & Jacob, C. M. A. (2001). Secondary hypogammaglobilinemia after use of carbamazepine: case report and review . Revista Do Hospital Das Clínicas, 56(6), 189-192. https://doi.org/10.1590/S0041-87812001000600006