Histological and immunohistochemical aspects of cutaneous leishmaniasis in nicaragua
Keywords:
Cutaneous leishmaniasis, Nicaragua, Pathology, Histological classification, Immunohistochemistry, Russel's bodiesAbstract
Sixty skin biopsies of fifty-eight non-treated patients with cutaneous leishmaniasis from Nicaragua were studied. Biopsies were classified according to Ridley's histopathologic groups: 36 (60%) were included in group B (diffuse necrosis), 14 in group C (focal necrosis), 7 (11.6%) in group D (reactive tuberculoid). Only three biopsies remained unclassified. None of our cases could be included in groups A and E. Immunohistochemistry disclosed in 17 cases Russel's bodies secreting IgM and only one IgG positive. There was no correlation between the histopathologic groups and the presence of Russel's bodies. However, we believe the presence of Russel's bodies help the diagnosis of leishmaniasis. Correlation between morphological patterns and the different leishmania species was also considered.Downloads
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Published
1987-08-01
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Section
Original Articles
How to Cite
Mariscotti, C., Barbareschi, M., Missoni, E., Morelli, R., Guevara, U., & Munguia-Barrera, J. (1987). Histological and immunohistochemical aspects of cutaneous leishmaniasis in nicaragua . Revista Do Instituto De Medicina Tropical De São Paulo, 29(4), 213-218. https://revistas.usp.br/rimtsp/article/view/28521