Cytomegalovirus perinatal infection in a public hospital of São Paulo city: a prospective study
Keywords:
CMV, Infecção perinatalAbstract
In order to demonstrate the occurrence of CMV perinatal infection in a middle socioeconomic class population, the authors conducted a 8-month prospective study in 37 children, not infected congenitally, born in a public hospital of São Paulo city, Prevalence of CMV-IgG antibodies in mothers, detected by immunoenzimatic assay (ELISA), was 92.7%. Survival analysis showed that the risk of acquiring CMV perinatal infection diagnosed by virus isolation in human fibroblasts was 30.9%. When the diagnostic method was detection of IgM class antibodies by indirect immunofluorescence the risk was 8.1% (p < 0.05). Milk samples inoculated in human fibroblasts failed to demonstrate the presence of virus. The infected children did not present any signal of disease in a 4-month follow-up.Downloads
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Published
1991-04-01
Issue
Section
Epidemiology
How to Cite
Machado, C. M., Fink, M. C. D. S., Vilas Boas, L. S., Sumita, L. M., Weinberg, A., Shiguematsu, K., Souza, I. C., Casanova, L. D., & Pannuti, C. S. (1991). Cytomegalovirus perinatal infection in a public hospital of São Paulo city: a prospective study . Revista Do Instituto De Medicina Tropical De São Paulo, 33(2), 159-166. https://revistas.usp.br/rimtsp/article/view/28809