Experimental models of mansonian schistosomiasis: Akodon arviculoides (Rodentia: Cricetidae)

Authors

  • José Roberto Machado e Silva Universidade do Estado do Rio de Janeiro; Faculdade de Ciências Médicas; Departamento de Patologia e Laboratórios
  • Regina Maria Figueiredo de Oliveira FIOCRUZ; IOC; Departamento de Biologia
  • Rosângela Rodrigues e Silva FIOCRUZ; IOC; Departamento de Biologia
  • Arnaldo Maldonado Jr. FIOCRUZ; IOC; Departamento de Biologia
  • Luis Rey FIOCRUZ; IOC; Departamento de Biologia

Keywords:

Akodon arviculoides, Esquistossomose experimental, Oograma, Roedores, Schistosoma mansoni

Abstract

The experimental infection of A. arviculoides through different routes of penetration of Schistosoma mansoni cercariae (Transcutaneous and subcutaneous) was studied by the cinetics of egg elimination in stools, by the recovery and localization of adult worms (in the portal system and the mesenteric veins) and through the quantitative egg count. It was shown that A. arviculoides infection is similar to the albino mice which served as control in relation to the efficiency of penetration routes, to the adult worms habitat and the egg count. These results suggest that other aspects of the host-parasite relationship should be evaluate so that A. arviculoides may be indicated as an alternative experimental model in schistosomiasis studies.

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Published

1991-08-01

Issue

Section

Original Article

How to Cite

Machado e Silva, J. R., Oliveira, R. M. F. de, Rodrigues e Silva, R., Maldonado Jr., A., & Rey, L. (1991). Experimental models of mansonian schistosomiasis: Akodon arviculoides (Rodentia: Cricetidae) . Revista Do Instituto De Medicina Tropical De São Paulo, 33(4), 257-261. https://revistas.usp.br/rimtsp/article/view/28832