Use of MAC-ELISA for evaluation of yellow fever vaccination

Authors

  • Rita M. Ribeiro Nogueira Fundação Oswaldo Cruz; Departamento de Virologia; Instituto Oswaldo Cruz
  • Hermann G. Schatzmayr Fundação Oswaldo Cruz; Departamento de Virologia; Instituto Oswaldo Cruz
  • Marize P. Miagostovich Fundação Oswaldo Cruz; Departamento de Virologia; Instituto Oswaldo Cruz
  • Silvia M. B. Cavalcanti Fundação Oswaldo Cruz; Departamento de Virologia; Instituto Oswaldo Cruz
  • Ricardo de Carvalho Fundação Oswaldo Cruz; Bio-Manguinhos

Keywords:

Yellow fever vaccinated, MAC-ELISA, PRNT

Abstract

An evaluation of the IgM antibody immune response against yellow fever using strain 17D was carried out by MAC-ELISA and PRNT. The results showed an agreement of 97% between both tests and the authors conclude that MAC-ELISA can be used as a specific and sensitive asssay to replace the PRNT for detecting yellow fever antibodies in human sera, after vaccination programs.

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Published

1992-10-01

Issue

Vol. 34 No. 5 (1992)

Section

Serology

How to Cite

Nogueira, R. M. R., Schatzmayr, H. G., Miagostovich, M. P., Cavalcanti, S. M. B., & Carvalho, R. de. (1992). Use of MAC-ELISA for evaluation of yellow fever vaccination . Revista Do Instituto De Medicina Tropical De São Paulo, 34(5), 447-450. https://revistas.usp.br/rimtsp/article/view/28965