Paracoccidioides brasiliensis isolated by hemoculture from a patient with AIDS

Authors

  • David J. Hadad Centro de Referência e Treinamento - AIDS
  • Maria de Fátima C. Pires Instituto Adolfo Lutz
  • Tereza C. Petry Centro de Referência e Treinamento - AIDS
  • Sandra Fernanda B. Orozco Instituto Adolfo Lutz
  • Marcia de. S. C. Melhem Instituto Adolfo Lutz
  • Roberto A. C. Paes Instituto Adolfo Lutz
  • Maria José S. M. Gianini Universidade Estadual Paulista Campus Araraquara

Keywords:

Paracoccidioides brasiliensis, Paracoccidioidomicose, Síndrome de imunodeficiência adquirida, SIDA

Abstract

A case of an AIDS-patient with positive blood culture for Paracoccidioides brasiliensis is reported. The patient was a 29 years old male born in Nova Londrina (Paraná State, Brazil) who presented splenomegaly and fever of unknown origin. Three blood cultures were performed, each one of them for aerobic bacteria, mycobacteria and fungi. Cultures for aerobic bacteria and mycobacteria were negative. However, the yeast phase P. brasiliensis was isolated from two cultures in BHI agar, 20 days after inoculation in Negroni medium. The patient was classified in group V according to the Centers for Disease Control (CDC) criteria for AIDS, due to a Pneumocystis carinii pneumonia. Treatment was discontinued due to an individual decision of the patient on the second dose of amphotericin B. This antibiotic was replaced by ketoconazole in the daily dose of 800 mg. The patient died one year after the isolation of P. brasiliensis on blood culture.

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Published

1992-12-01

Issue

Vol. 34 No. 6 (1992)

Section

Case Report

How to Cite

Hadad, D. J., Pires, M. de F. C., Petry, T. C., Orozco, S. F. B., Melhem, M. de. S. C., Paes, R. A. C., & Gianini, M. J. S. M. (1992). Paracoccidioides brasiliensis isolated by hemoculture from a patient with AIDS . Revista Do Instituto De Medicina Tropical De São Paulo, 34(6), 565-567. https://revistas.usp.br/rimtsp/article/view/28982