Serological and parasitological evaluation of goats, experimentally inoculated with Trypanosoma cruzi

Abstract

The experimental infection by Trypanosoma cruzi was studied in nine young goats. These animals were inoculated by intraperitoneal route with 10³ trypo-mastigotes/Kg body weight with strains 147 (Group 1) and 229 (Group 2), isolated from chronic Chagasic patients proceeding from Bambuí, Minas Gerais, Brazil. The infected animals were submitted to fresh blood examinations, xenodiagnosis, hemoculture and serology (IFAT and ELISA). The follow up of T cruzi infection ranged from 7 to 30 months and it was possible to note a markable difference concerning the course of infection between the two groups. The parasite was visualized, for the first time in experimentally infected goats in the acute period through fresh blood examinations and xenodiagnosis and through hémoculture and xenodiagnosis during the chronic period of the Chagasic infection. These results suggest that, under some epidemiological conditions, goats may be important in the sylvatic and peridomiciliar transmission cycles of T. cruzi specially young animals.