Gelatin particle indirect agglutination test for serodiagnosis of schistosomiasis: comparative study with enzyme-linked immunosorbent assay

Authors

  • Jun Kobayashi University of the Ryukyus; School of Medicine; Department of Parasitology
  • Flair José Carrilho University of São Paulo; School of Medicine; Department of Gastroenterology
  • Tetsu Shimabukuro University of Campinas; Gastrocentro; Laboratório de Imuno-Parasitologia
  • Luiz Caetano da Silva University of São Paulo; Instituto de Medicina Tropical de São Paulo
  • Elza Cotrim Soares University of Campinas; Gastrocentro; Laboratório de Imuno-Parasitologia
  • Nancy Fusae Nishimura University of Campinas; Gastrocentro; Laboratório de Imuno-Parasitologia
  • Pedro Paulo Chieffi University of São Paulo; School of Medicine; Department of Preventive Medicine
  • Yoshiya Sato University of the Ryukyus; School of Medicine; Research Center of Comprehensive Medicine

Keywords:

Schistosoma mansoni, Serodiagnosis, GPAT (gelatin particle agglutination test), ELISA

Abstract

A new serological test, the gelatin particle agglutination test (GPAT), was used for the serodiagnosis of schistosomiasis mansoni. This technique showed the sensitivity (90.6%) and specificity (97.8%) close to those of enzyme-linked immunosorbent assay. The GPAT can be easily and rapidly performed without specialized equipment, by using lyophilized antigen-coated gelatin particles. The test also seems to be useful for mass screening of Schistosoma infection in field conditions.

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Published

1994-10-01

Issue

Vol. 36 No. 5 (1994)

Section

Serology

How to Cite

Kobayashi, J., Carrilho, F. J., Shimabukuro, T., Silva, L. C. da, Soares, E. C., Nishimura, N. F., Chieffi, P. P., & Sato, Y. (1994). Gelatin particle indirect agglutination test for serodiagnosis of schistosomiasis: comparative study with enzyme-linked immunosorbent assay . Revista Do Instituto De Medicina Tropical De São Paulo, 36(5), 389-394. https://revistas.usp.br/rimtsp/article/view/29189