Molecular typing of Candida albicans strains isolated from nosocomial candidemia

Authors

  • Maria Luiza Moretti Branchini Universidade Estadual de Campinas; Faculty of Medical Sciences; Infectious Diseases Division
  • Débora de Cassia Pires Geiger Universidade Federal do Estado de São Paulo; Escola Paulista de Medicina; Infectious Diseases Division
  • Olga Fischman Universidade Federal do Estado de São Paulo; Escola Paulista de Medicina; Celular Biology Division
  • Antonio Carlos Pignatari Universidade Federal do Estado de São Paulo; Escola Paulista de Medicina; Infectious Diseases Division

Keywords:

Candida albicans, Nosocomial candidemia, Pulsed-field gel electrophoresis, Molecular typing

Abstract

Yeasts of the genus Candida have been recognized as important microorganisms responsible for nosocomial fungemia. Six blood-stream and two intravenous central catheter C. albicans strains were isolated from eight patients and studied by electrophoretic karyotyping of chromosomal DNA by pulsed-field gel electrophoresis. Seven chromosomal DNA profiles were identified. Two patients showed isolates with the same profile, suggesting nosocomial transmission. Karyotyping of C. albicans revealed an excellent discriminatory power among the isolates and may therefore be useful in the study of nosocomial candidemia.

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Published

1995-12-01

Issue

Vol. 37 No. 6 (1995)

Section

Mycology

How to Cite

Branchini, M. L. M., Geiger, D. de C. P., Fischman, O., & Pignatari, A. C. (1995). Molecular typing of Candida albicans strains isolated from nosocomial candidemia . Revista Do Instituto De Medicina Tropical De São Paulo, 37(6), 483-487. https://revistas.usp.br/rimtsp/article/view/29315