Distribution of hepatitis C virus genotypes among blood donors from mid-west region of Brazil

Authors

  • Regina M.B. Martins Universidade Federal de Goiás; Instituto de Patologia Tropical e Saúde Pública
  • Sheila A. Teles Universidade Federal de Goiás; Instituto de Patologia Tropical e Saúde Pública
  • Nara R. Freitas Universidade Federal de Goiás; Instituto de Patologia Tropical e Saúde Pública
  • Ana R.C. Motta-Castro Universidade Federal de Mato Grosso do Sul; Departamento de Farmácia e Bioquímica
  • Francisco J.D. Souto Universidade Federal de Mato Grosso; Núcleo de Doenças Infecciosas e Tropicais de Mato Grosso
  • Aparecida Mussi Universidade Federal de Mato Grosso; Núcleo de Doenças Infecciosas e Tropicais de Mato Grosso
  • Regina M.S. Amorim Universidade de Brasília; Departamento de Biologia Celular
  • Cláudia R.F. Martins Universidade de Brasília; Departamento de Biologia Celular

Keywords:

Hepatitis C virus, Genotypes, Blood donors, Brazil

Abstract

In order to investigate the hepatitis C virus (HCV) genotypes in mid-west region of Brazil, 250 anti-HCV positive blood donors were studied. Among them, the anti-HCV serological status was confirmed in 205 (82%). HCV RNA was detected in 165 samples, which were genotyped. HCV types 1, 2 and 3 were found in 67.9%, 3% and 29.1% of the donors, respectively. In Goiás state, subtype 1a (50%) was the most prevalent, followed by subtypes 3a (30.9%) and 1b (16.7%). In Mato Grosso state, subtype 1a was also predominant (41%), followed by subtypes 1b (29.5%) and 3a (25%). In Mato Grosso do Sul state, subtypes 1a and 1b were detected equally (36.8%), followed by 3a (21.1%). Subtype 2b was rare (2.4%, 4.5% and 5.3%, respectively). In Distrito Federal, subtype 3a (39%) was more frequent than 1a (31.7%) and the remaining (29.3%) belonged to subtype 1b.

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Published

2006-02-01

Issue

Section

Brief Communication

How to Cite

Martins, R. M., Teles, S. A., Freitas, N. R., Motta-Castro, A. R., Souto, F. J., Mussi, A., Amorim, R. M., & Martins, C. R. (2006). Distribution of hepatitis C virus genotypes among blood donors from mid-west region of Brazil . Revista Do Instituto De Medicina Tropical De São Paulo, 48(1), 53-55. https://revistas.usp.br/rimtsp/article/view/30970