Chronic disseminated histoplasmosis with lesions restricted to the mouth: case report

Authors

  • Antonio Carlos F. do Valle Fundação Oswaldo Cruz; Instituto de Pesquisa Clínica Evandro Chagas; Department of Infectious Diseases
  • Luiz Carlos Moreira Fundação Oswaldo Cruz; Instituto de Pesquisa Clínica Evandro Chagas; Department of Infectious Diseases
  • Rodrigo Almeida-Paes Fundação Oswaldo Cruz; Instituto de Pesquisa Clínica Evandro Chagas; Department of Micro-Immuno-Parasitology
  • João S. Moreira Fundação Oswaldo Cruz; Instituto de Pesquisa Clínica Evandro Chagas; Department of Infectious Diseases
  • Cláudia V. Pizzini Fundação Oswaldo Cruz; Instituto de Pesquisa Clínica Evandro Chagas; Department of Micro-Immuno-Parasitology
  • Mauro de Medeiros Muniz Fundação Oswaldo Cruz; Instituto de Pesquisa Clínica Evandro Chagas; Department of Micro-Immuno-Parasitology
  • Rosely M. Zancopé-Oliveira Fundação Oswaldo Cruz; Instituto de Pesquisa Clínica Evandro Chagas; Department of Micro-Immuno-Parasitology

Keywords:

Histoplasmosis, Oral lesions, Fungal disease

Abstract

We report a rare case of chronic disseminated histoplasmosis with several ulcerated lesions in the oral cavity in an alcoholic patient without human immunodeficiency virus infection, with no detectable signs and symptoms of systemic disease or extraoral manifestations. Histopathological analysis revealed chronic inflammatory process with granulomas containing Histoplasma-like organisms. The isolation of Histoplasma capsulatum provided the definitive diagnosis. Treatment with itraconazole resulted in complete remission of oral lesions. As far we aware, this is the second case report of oral histoplasmosis in an HIV negative patient described in Brazil.

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Published

2006-04-01

Issue

Vol. 48 No. 2 (2006)

Section

Case Reports

How to Cite

Valle, A. C. F. do, Moreira, L. C., Almeida-Paes, R., Moreira, J. S., Pizzini, C. V., Muniz, M. de M., & Zancopé-Oliveira, R. M. (2006). Chronic disseminated histoplasmosis with lesions restricted to the mouth: case report . Revista Do Instituto De Medicina Tropical De São Paulo, 48(2), 113-116. https://revistas.usp.br/rimtsp/article/view/30984