Adrenal function in 23 children with paracoccidioidomycosis

Authors

  • Ricardo Mendes Pereira Universidade Estadual de Campinas; Faculdade de Ciências Médicas; Departamento de Pediatria
  • Gil Guerra-Júnior Universidade Estadual de Campinas; Faculdade de Ciências Médicas; Departamento de Pediatria
  • Antonia Terezinha Tresoldi Universidade Estadual de Campinas; Faculdade de Ciências Médicas; Departamento de Pediatria

Keywords:

Paracoccidioidomycosis, Paracoccidioides brasiliensis, Children, Adrenal, Cortisol and ACTH

Abstract

Adrenal involvement by Paracoccidioides brasiliensis was described at necropsies and in many clinical studies, but only in adults. Therefore, the aim of this study was to evaluate adrenal function in children with paracoccidioidomycosis. Twenty-three children with the systemic form of paracoccidioidomycosis were evaluated and divided in two Groups: Group A (n = 8) included children before treatment and Group B (n = 15) children after the end of treatment. Plasma cortisol (basal and after ACTH test), ACTH, renin activity, aldosterone, sodium and potassium were measured. They were within normal range in all cases, except for renin activity and aldosterone, which were elevated in some cases. Group A patients showed basal and post-ACTH cortisol levels significantly greater than Group B patients. The results showed that adrenal function was not compromised in these children with paracoccidioidomycosis.

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Published

2006-12-01

Issue

Vol. 48 No. 6 (2006)

Section

Paracoccidioidomycosis

How to Cite

Pereira, R. M., Guerra-Júnior, G., & Tresoldi, A. T. (2006). Adrenal function in 23 children with paracoccidioidomycosis . Revista Do Instituto De Medicina Tropical De São Paulo, 48(6), 333-336. https://revistas.usp.br/rimtsp/article/view/31039