Identification of Paracoccidioides brasiliensis in adrenal glands biopsies of two patients with paracoccidioidomycosis and adrenal insufficiency

Authors

  • Carlos Andrés Agudelo Corporación para Investigaciones Biológicas; Medical and Experimental Mycology Unit
  • Carolina Muñoz Universidad Pontificia Bolivariana; School of Medicine
  • Alex Ramírez Universidad Pontificia Bolivariana; School of Medicine
  • Jonhairo Gutierrez Hospital Pablo Tobón Uribe; Laboratory Service; Departments of Internal medicine Critical Care
  • Santiago Velez Universidad Pontificia Bolivariana; School of Medicine
  • Juan Camilo Perez Hospital Pablo Tobón Uribe; Laboratory Service; Departments of Internal medicine Critical Care
  • Alejandro Velez Hospital Pablo Tobón Uribe; Laboratory Service; Departments of Internal medicine Critical Care
  • Angela María Tobon Hospital La María; Internal Medicine
  • Angela Restrepo Corporación para Investigaciones Biológicas; Medical and Experimental Mycology Unit

Keywords:

Paracoccidioidomycosis, Adrenal insufficiency, Cortisol

Abstract

The authors report two cases of adrenal insufficiency secondary to infiltration of the adrenal glands by Paracoccidioides brasiliensis. The first patient had been treated for a chronic multifocal form of paracoccidiodomycosis 11 years ago. The diagnosis of the mycosis was done simultaneous with that of the adrenal insufficiency in the second patient. In both patients the diagnosis was done by direct visualization of fungus in adrenal biopsies. They were treated with hormonal supplements and itraconazol by 12 and six months, without relapses during the follow-up period.

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Published

2009-02-01

Issue

Vol. 51 No. 1 (2009)

Section

Microbiology

How to Cite

Agudelo, C. A., Muñoz, C., Ramírez, A., Gutierrez, J., Velez, S., Perez, J. C., Velez, A., Tobon, A. M., & Restrepo, A. (2009). Identification of Paracoccidioides brasiliensis in adrenal glands biopsies of two patients with paracoccidioidomycosis and adrenal insufficiency . Revista Do Instituto De Medicina Tropical De São Paulo, 51(1), 45-48. https://revistas.usp.br/rimtsp/article/view/31242