Profile of patients with Baggio-Yoshinari Syndrome admitted at "Instituto de Infectologia Emilio Ribas"

Authors

  • Emy Akiyama Gouveia Hospital Estadual Mário Covas
  • Mayra Fernanda Alves Universidade de São Paulo; Faculdade de Medicina; Hospital das Clínicas; Laboratório de Investigação Médica em Reumatologia
  • Elenice Mantovani Universidade de São Paulo; Faculdade de Medicina; Hospital das Clínicas; Laboratório de Investigação Médica em Reumatologia
  • Luiza Keiko Oyafuso Instituto de Infectologia Emílio Ribas
  • Virgínia Lucia Nazario Bonoldi Universidade de São Paulo; Faculdade de Medicina; Hospital das Clínicas; Laboratório de Investigação Médica em Reumatologia
  • Natalino Hajime Yoshinari Universidade de São Paulo; Faculdade de Medicina; Hospital das Clínicas; Laboratório de Investigação Médica em Reumatologia

Keywords:

Lyme Disease, Lyme disease-like illness, Baggio-Yoshinari Syndrome, Tick-borne diseases, Borrelia burgdorferi, Brazil

Abstract

The aim of this study was to evaluate the epidemiological, clinical and laboratorial profile of patients with Baggio-Yoshinari Syndrome (BYS), who underwent internment at the Instituto de Infectologia Emilio Ribas in São Paulo, Brazil, during the period from July 1990 to July 2006. BYS is a new Brazilian tick-borne disease caused by Borrelia burgdorferi sensu lato microorganisms that resembles features of Lyme disease (LD), except for its epidemiological, clinical and laboratorial particularities. From 60 patients' records with positive serology to B. burgdorferi done by ELISA and Western-blotting methods, 19 cases were diagnosed as having BYS, according to criteria adopted at LIM-17 HCFMUSP, the Brazilian Reference Laboratory for the research of BYS. The other 41 remaining patients displayed miscellaneous infections or auto-immune processes. The beginning of symptoms in BYS group varied from one day to six years, from the onset of the disease. Four of 19 patients were included in acute disease stage, and 15 in latent. General unspecific symptoms were identified in almost all cases, with high frequencies of fever (78.9%) and lymphadenomegaly (36.8%). Six patients had skin lesions (31.5%); six arthralgia or arthritis (31.5%) and eight neurological symptoms (42%). Interestingly, two patients showed antibodies directed to B. burgdorferi exclusively in cerebrospinal fluid. Since BYS is a new emergent Brazilian zoonosis and its diagnosis is sometimes complex, all the new knowledge about BYS must be scattered to Brazilian Medical specialists, aiming to teach them how to diagnose this amazing tick-borne disease and to avoid its progression to chronic irreversible sequels

Downloads

Download data is not yet available.

Downloads

Published

2010-12-01

Issue

Section

Microbiology

How to Cite

Gouveia, E. A., Alves, M. F., Mantovani, E., Oyafuso, L. K., Bonoldi, V. L. N., & Yoshinari, N. H. (2010). Profile of patients with Baggio-Yoshinari Syndrome admitted at "Instituto de Infectologia Emilio Ribas" . Revista Do Instituto De Medicina Tropical De São Paulo, 52(6), 297-303. https://revistas.usp.br/rimtsp/article/view/31358