Antibody levels to hantavirus in inhabitants of western Santa Catarina State, Brazil

Authors

  • William Marciel de Souza Universidade de São Paulo; School of Medicine of Ribeirão Preto; Virology Research Center
  • Alex Martins Machado Universidade de São Paulo; School of Medicine of Ribeirão Preto; Virology Research Center
  • Geonildo Rodrigo Disner Universidade do Oeste de Santa Catarina; Department of Biological Sciences and Health
  • Everton Boff Universidade do Oeste de Santa Catarina; Department of Biological Sciences and Health
  • Aline Rafaela da Silva Rodrigues Machado Universidade de São Paulo; School of Medicine of Ribeirão Preto; Virology Research Center
  • Michelly de Padua Universidade de São Paulo; School of Medicine of Ribeirão Preto; Virology Research Center
  • Luiz Tadeu Moraes Figueiredo Universidade de São Paulo; School of Medicine of Ribeirão Preto; Virology Research Center
  • Gustavo Borba de Miranda Universidade do Oeste de Santa Catarina; Department of Biological Sciences and Health

Keywords:

Hantavirus, Epidemiology, Brazil, Argentina, Santa Catarina

Abstract

Hantavirus cardiopulmonary syndrome (HCPS) is an infectious disease caused by hantaviruses of the family Bunyaviridae, and is transmitted by aerosols of excreta of infected rodents. The aim of the present study was to determine antibody levels to hantavirus in the population that lives at frontier of Brazil and Argentina. Participated of the study 405 individuals living in the municipalities of Bandeirante, Santa Helena, Princesa and Tunapolis, state of Santa Catarina, Brazil. IgG antibodies to hantavirus were analyzed in sera by an ELISA that uses a recombinant N protein of Araraquara hantavirus as antigen. The results were also confirmed by immunofluorescent test. Eight individuals showed antibodies to hantavirus (1.97% positivity), with serum titers ranging from 100 to 800. Six seropositives were males, older than 30 years and farmers. Our results reinforce previous data on hantavirus circulation and human infections in the southern border of Brazil with Argentina.

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Published

2012-08-01

Issue

Section

Virology

How to Cite

Souza, W. M. de, Machado, A. M., Disner, G. R., Boff, E., Machado, A. R. da S. R., Padua, M. de, Figueiredo, L. T. M., & Miranda, G. B. de. (2012). Antibody levels to hantavirus in inhabitants of western Santa Catarina State, Brazil. Revista Do Instituto De Medicina Tropical De São Paulo, 54(4), 193-196. https://revistas.usp.br/rimtsp/article/view/48388