RESOLUTION OF CUTANEOUS LEISHMANIASIS AFTER ACUTE ECZEMA DUE TO INTRALESIONAL MEGLUMINE ANTIMONIATE

Authors

  • Erica de Camargo Ferreira e Vasconcellos Oswaldo Cruz Foundation; Evandro Chagas Clinical Research Institute; Leishmaniasis Surveillance Laboratory
  • Maria Inês Fernandes Pimentel Oswaldo Cruz Foundation; Evandro Chagas Clinical Research Institute; Leishmaniasis Surveillance Laboratory
  • Cláudia Maria Valete-Rosalino Rio de Janeiro Federal University; Otorhinolaryngology and Ophthalmology Department
  • Maria de Fátima Madeira Oswaldo Cruz Foundation; Evandro Chagas Clinical Research Institute; Leishmaniasis Surveillance Laboratory
  • Armando de Oliveira Schubach Our State Scientist from Carlos Chagas Filho Foundation for the Research Support in Rio de Janeiro State (FAPERJ)

Abstract

We report a case of a 42 year-old female, who came to a leishmaniasis reference center in Rio de Janeiro, Brazil, presenting a cutaneous leishmaniasis lesion in the right forearm. Treatment with low-dose intramuscular meglumine antimoniate (MA) (5 mg Sb5+/kg/day) was initiated, with improvement after 28 days, although with the development of generalized eczema. After 87 days, the lesion worsened. Patient refused treatment with amphotericin B. MA was then infiltrated in the lesion, in two sessions, resulting in local eczema, with bullae formation; however, twenty days after, both the ulcer and eczema receded. Intralesional administration of MA should be used carefully when previous cutaneous hypersensitivity is detected.

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Published

2014-07-01

Issue

Section

Case Report

How to Cite

Vasconcellos, E. de C. F. e, Pimentel, M. I. F., Valete-Rosalino, C. M., Madeira, M. de F., & Schubach, A. de O. (2014). RESOLUTION OF CUTANEOUS LEISHMANIASIS AFTER ACUTE ECZEMA DUE TO INTRALESIONAL MEGLUMINE ANTIMONIATE . Revista Do Instituto De Medicina Tropical De São Paulo, 56(4), 361-362. https://revistas.usp.br/rimtsp/article/view/84436