Long-acting antipsychotics in the maintenance treatment of schizophrenia: Part I. Foundations of its development, benefits and acceptance level in different countries and cultures

Authors

  • Luiz Paulo de C. Bechelli Université Claude Bernard

DOI:

https://doi.org/10.1590/S0104-11692003000300012

Keywords:

antipsychotic, long-acting antipsychotic, depot antipsychotic, schizophrenia, adherence

Abstract

In this study, the foundations of long-acting antipsychotics development, the adherence to treatment, the factors that make difficult the following of the prescription and their consequences, the benefits and acceptance of long-acting antipsychotics are revised. Based on the data obtained from the first part of this study, the following issues must be highlighted: the non-adherence treatment level in schizophrenia is about 60%. Considering schizophrenia a chronic disease with high relapse risk, the maintenance treatment helps its control. The long-acting antipsychotics were developed exactly for the purpose of guaranteeing the administration of the medication and its regularity, which are essential requirements in preventing a relapse. In spite of the immensurable benefits of the long-acting antipsychotics, several factors have contributed to their usage below their potential.

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Published

2003-06-01

Issue

Vol. 11 No. 3 (2003)

Section

Review Articles

License

RLAE’s authorship concept is based on the substantial contribution by each of the individuals listed as authors, mainly in terms of conceiving and planning the research project, collecting or analyzing and interpreting data, writing and critical review. Indication of authors’ names under the article title is limited to six. If more, authors are listed on the online submission form under Acknowledgements. The possibility of including more than six authors will only be examined on multicenter studies, considering the explanations presented by the authors.
Including names of authors whose contribution does not fit into the above criteria cannot be justified. Those names can be included in the Acknowledgements section.
 Authors are fully responsible for the concepts disseminated in their manuscripts, which do not necessarily reflect the editors’ and editorial board’s opinion.

 

How to Cite

Long-acting antipsychotics in the maintenance treatment of schizophrenia: Part I. Foundations of its development, benefits and acceptance level in different countries and cultures. (2003). Revista Latino-Americana De Enfermagem, 11(3), 341-349. https://doi.org/10.1590/S0104-11692003000300012