Factors associated to chronic kidney disease in people living with HIV/AIDS

Authors

  • Priscila Silva Pontes Universidade de São Paulo. Escola de Enfermagem de Ribeirão Preto. Centro Colaborador da OPAS/OMS para o Desenvolvimento da Pesquisa em Enfermagem http://orcid.org/0000-0002-1318-8431
  • Antonio Ruffino-Netto Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Medicinal Social. http://orcid.org/0000-0001-9770-4896
  • Luciana Kusumota Universidade de São Paulo. Escola de Enfermagem de Ribeirão Preto. Centro Colaborador da OPAS/OMS para o Desenvolvimento da Pesquisa em Enfermagem http://orcid.org/0000-0001-9290-3722
  • Christefany Régia Braz Costa Universidade de São Paulo. Escola de Enfermagem de Ribeirão Preto. Centro Colaborador da OPAS/OMS para o Desenvolvimento da Pesquisa em Enfermagem http://orcid.org/0000-0001-6124-8243
  • Elucir Gir Universidade de São Paulo. Escola de Enfermagem de Ribeirão Preto. Centro Colaborador da OPAS/OMS para o Desenvolvimento da Pesquisa em Enfermagem http://orcid.org/0000-0002-3757-4900
  • Renata Karina Reis Universidade de São Paulo. Escola de Enfermagem de Ribeirão Preto. Centro Colaborador da OPAS/OMS para o Desenvolvimento da Pesquisa em Enfermagem http://orcid.org/0000-0002-0681-4721

DOI:

https://doi.org/10.1590/1518-8345.3553.3331

Keywords:

HIV, Chronic Renal Insufficiency, Glomerular Filtration Rate, Highly Active Antiretroviral Therapy, Risk Factors, Comorbidity

Abstract

Objective: to analyze the factors associated to chronic kidney disease in people living with HIV (PLHIV). Method: a paired case-control study (4 controls for each case) carried out in a specialized care service in the Southeastern of Brazil, by analyzing PLHIV medical records. The sample consisted of 85 participants, corresponding to 17 cases and 68 controls. Pearson’s chi-square test (Χ2) and Fisher’s exact test, logistic regression, Odds Ratio (OR), 95% Confidence Interval (CI) and p<0.05 were used. SPSS version 25.0 and R Core Team, 2018 version 3.5.1 were used. Results: the factors associated with chronic kidney disease identified in this study were the following: presence of Systemic Arterial Hypertension [OR=5.8, CI (95%)=1.84-18.42, p=0.001] and use of nephrotoxic anti-retrovirals in the previous therapeutic regimen [OR=3.3, CI (95%)=1.105-10.221, p=0.028]. On the other hand, age below 40 years old [OR: 0.122, CI (95%)=0.015-0.981, p=0.022] was identified as a protective factor. Conclusion: the PLHIV under study have multi-factorial exposure associated with chronic kidney disease. However, knowing these factors helps to identify the existing risks and/or renal dysfunction, in addition to supporting the clinical decision of the health professionals who directly assist them.

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Published

2020-02-23

Issue

Vol. 28 (2020)

Section

Original Articles

License

Copyright (c) 2020 Revista Latino-Americana de Enfermagem

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How to Cite

Factors associated to chronic kidney disease in people living with HIV/AIDS. (2020). Revista Latino-Americana De Enfermagem, 28, e3331. https://doi.org/10.1590/1518-8345.3553.3331