Liver frailty and impact of liver transplants on transplanted patients’ health
DOI:
https://doi.org/10.1590/1518-8345.7330.4564Keywords:
Frailty; Liver Cirrhosis; Liver Transplantation; Alcoholics; Nursing; RehabilitationAbstract
Objective: to analyse the Liver Frailty Index in a cohort of patients from their inclusion in the waiting list to one year after the liver transplant. Method: a cohort study with patients included in a liver transplant waiting list from January 2020 to December 2021. The variables were analysed and the hypothesis were contrasted by means of the Mann-Whitney U and Spearman’s correlation test, a paired measures test and multivariate analysis. Results: the sample consisted in n=51 patients with a mean age of 57.20 years old (SD=9.70), with 74.50% of men. The mean pre-transplant Liver Frailty index was 3.71 (SD=0.74), reaching higher values in patients with advanced liver disease (p=0.004), alcohol-related etiology (p=0.039) and unemployed (p=0.014). Liver frailty improved after the transplant (p<0.001), keeping a directly proportional correlation with age (p=0.014). Conclusion: advanced liver disease, etiology related to alcohol and time in the waiting list exert impacts on liver frailty during the liver transplant process. Older liver transplanted patients are more frail.
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