Nasopharyngeal colonization with methicillin-resistant staphylococcus aureus and mortality among patients in an intensive care unit

Authors

  • Cristiane Ravagnani Fortaleza Universidade Estadual Paulista Júlio de Mesquita Filho; Faculdade de Medicina de Botucatu
  • Edson Carvalho de Melo Hospital Estadual de Bauru
  • Carlos Magno Castelo Branco Fortaleza Universidade Estadual Paulista Júlio de Mesquita Filho; Faculdade de Medicina de Botucatu

DOI:

https://doi.org/10.1590/S0104-11692009000500013

Keywords:

Staphylococcus aureus, intensive care units, mortality

Abstract

Nasopharyngeal colonization with Methicillin-resistant Staphylococcus aureus (MRSA) is common in critically ill patients, but its effect on patient prognosis is not fully elucidated. A retrospective cohort study was carried out enrolling 122 patients from an intensive care unit who were screened weekly for nasopharyngeal colonization with MRSA. The outcomes of interest were: general mortality and mortality by infection. Several exposure variables (severity of illness, procedures, intercurrences and MRSA nasopharyngeal colonization) were analyzed through univariate and multivariable models. Factors significantly associated with mortality in general or due to infection were: APACHE II and lung disease. The performance of surgery predicted favorable outcomes. MRSA colonization did not predict mortality in general (OR=1.02; 95%CI=0.35-3.00; p=0.97) or by infectious causes (OR=0.96; 95%CI=0.33-2.89; p=0.96). The results suggest that, in the absence of severity of illness factors, colonization with MRSA is not associated with unfavorable outcomes.

Downloads

Download data is not yet available.

Downloads

Published

2009-10-01

Issue

Vol. 17 No. 5 (2009)

Section

Original Articles

License

RLAE’s authorship concept is based on the substantial contribution by each of the individuals listed as authors, mainly in terms of conceiving and planning the research project, collecting or analyzing and interpreting data, writing and critical review. Indication of authors’ names under the article title is limited to six. If more, authors are listed on the online submission form under Acknowledgements. The possibility of including more than six authors will only be examined on multicenter studies, considering the explanations presented by the authors.
Including names of authors whose contribution does not fit into the above criteria cannot be justified. Those names can be included in the Acknowledgements section.
 Authors are fully responsible for the concepts disseminated in their manuscripts, which do not necessarily reflect the editors’ and editorial board’s opinion.

 

How to Cite

Nasopharyngeal colonization with methicillin-resistant staphylococcus aureus and mortality among patients in an intensive care unit. (2009). Revista Latino-Americana De Enfermagem, 17(5), 677-682. https://doi.org/10.1590/S0104-11692009000500013