Infusion of Hematopoietic Stem Cells: Types, Characteristics, Adverse and Transfusion Reactions and the Implications for Nursing

Authors

  • Ana Carolina de Jesus Vieira Curcioli Universidade de São Paulo; Escola de Enfermagem de Ribeirão Preto
  • Emilia Campos de Carvalho Universidade de São Paulo; Escola de Enfermagem de Ribeirão Preto

DOI:

https://doi.org/10.1590/S0104-11692010000400009

Keywords:

Hematopoietic Stem Cell Transplantation^i1^sAdverse Effe, Blood Component Transfusion, Nursing

Abstract

Hematopoietic stem cell infusion is an important procedure in Hematopoietic Stem Cell Transplantation (HSCT). This study identifies transfusion and other adverse reactions that can occur during infusion and the nursing care related to the procedure. This epidemiologic study used transplantations performed between 2006 and 2008. A total of 166 transplantations were performed: 114 were autologous, 47 allogeneic and five haploidentical. Three transfusion reactions and 96 adverse reactions were observed. Adverse reactions were related to the presence of cryoprotectant, though the infusion rate and quantity of infused cryoprotectant were not related to the occurrence of reactions. The products were fresh and infused within the recommended time when transfusion reactions occurred. In regard to cell source, lower engraftment time was found in peripheral blood. Nursing documentation is relevant for patients' safety as well to planning an infusion in order to minimize the occurrence of reactions.

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Published

2010-08-01

Issue

Vol. 18 No. 4 (2010)

Section

Original Articles

License

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Including names of authors whose contribution does not fit into the above criteria cannot be justified. Those names can be included in the Acknowledgements section.
 Authors are fully responsible for the concepts disseminated in their manuscripts, which do not necessarily reflect the editors’ and editorial board’s opinion.

 

How to Cite

Infusion of Hematopoietic Stem Cells: Types, Characteristics, Adverse and Transfusion Reactions and the Implications for Nursing . (2010). Revista Latino-Americana De Enfermagem, 18(4), 716-724. https://doi.org/10.1590/S0104-11692010000400009