Clinical application of Chamomilla recutita in phlebitis: dose response curve study

Authors

  • Paula Elaine Diniz dos Reis Universidade de Brasília
  • Emilia Campos de Carvalho Universidade de São Paulo; Escola de Enfermagem de Ribeirão Preto
  • Paula Carolina Pires Bueno Universidade de São Paulo; Escola de Enfermagem de Ribeirão Preto
  • Jairo Kenupp Bastos Universidade de São Paulo; Faculdade de Ciências Farmacêuticas de Ribeirão Preto

DOI:

https://doi.org/10.1590/S0104-11692011000100002

Keywords:

Matricaria, Phlebitis, Dose-Response Relationship, Drug

Abstract

This experimental and dose-response curve study aimed to carry out the quality control of the Chamomilla recutita sample, as well as to estimate the ideal dose, for anti-inflammatory effect, of the extract of its capitula, in patients with phlebitis due to peripheral intravenous infusion of antineoplastic chemotherapy and to evaluate the toxicity of this extract in human beings. The therapeutic efficacy, concerning the anti-inflammatory potential, of different doses of Chamomilla recutita extract were analyzed and compared in 25 patients. The time of regression of phlebitis was shorter for groups with 2.5% concentration (mean=29.2h, standard deviation = 8.98) and 5% concentration (mean = 38.8h, standard deviation = 17.47). Local toxicity was almost not observed. This research contributes to the innovation of the nursing clinical practice, since it suggests an alternative for the treatment of phlebitis through the clinical use of phytotherapeutic drugs.

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Published

2011-02-01

Issue

Vol. 19 No. 1 (2011)

Section

Original Articles

License

RLAE’s authorship concept is based on the substantial contribution by each of the individuals listed as authors, mainly in terms of conceiving and planning the research project, collecting or analyzing and interpreting data, writing and critical review. Indication of authors’ names under the article title is limited to six. If more, authors are listed on the online submission form under Acknowledgements. The possibility of including more than six authors will only be examined on multicenter studies, considering the explanations presented by the authors.
Including names of authors whose contribution does not fit into the above criteria cannot be justified. Those names can be included in the Acknowledgements section.
 Authors are fully responsible for the concepts disseminated in their manuscripts, which do not necessarily reflect the editors’ and editorial board’s opinion.

 

How to Cite

Clinical application of Chamomilla recutita in phlebitis: dose response curve study . (2011). Revista Latino-Americana De Enfermagem, 19(1), 03-10. https://doi.org/10.1590/S0104-11692011000100002