Pharmacological adherence to oral anticoagulant and factors that influence the international normalized ratio stability

Authors

  • Christiane Wahast Ávila Universidade Federal do Rio Grande do Sul; Escola de Enfermagem; Hospital de Clínicas de Porto Alegre
  • Graziella Badin Aliti Hospital de Clínicas de Porto Alegre
  • Maria Karolina Ferreira Feijó Universidade Federal do Rio Grande do Sul; Escola de Enfermagem; Hospital de Clínicas de Porto Alegre
  • Eneida Rejane Rabelo Universidade Federal do Rio Grande do Sul; Escola de Enfermagem

DOI:

https://doi.org/10.1590/S0104-11692011000100004

Keywords:

Anticoagulants, International Normalized Ratio, Monitoring, Ambulatory

Abstract

Cross-sectional study developed to relate the international normalized ratio (INR), used as a parameter to monitor the levels of blood clotting, stability to adherence, age, level of education, socioeconomic level, interaction with other drugs, comorbidities, vitamin K intake, anticoagulation time and drug cost. 156 patients were included, mean age 57±13 years, (53.8%) male, 61 (39.1%) had high adherence, 91 (58.3%) medium and 4 (2.6%) low adherence to treatment, 117 (75%) had INR stability up to 50% and 39 (25%) >; 75%, patients with shorter time of anticoagulation presented higher stability, those who spent less on the drug remained more stable and had better adherence. It was concluded that more than 90% of patients had high and medium adherence and that the anticoagulation time and drug cost were the factors related to the anticoagulation stability.

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Published

2011-02-01

Issue

Vol. 19 No. 1 (2011)

Section

Original Articles

License

RLAE’s authorship concept is based on the substantial contribution by each of the individuals listed as authors, mainly in terms of conceiving and planning the research project, collecting or analyzing and interpreting data, writing and critical review. Indication of authors’ names under the article title is limited to six. If more, authors are listed on the online submission form under Acknowledgements. The possibility of including more than six authors will only be examined on multicenter studies, considering the explanations presented by the authors.
Including names of authors whose contribution does not fit into the above criteria cannot be justified. Those names can be included in the Acknowledgements section.
 Authors are fully responsible for the concepts disseminated in their manuscripts, which do not necessarily reflect the editors’ and editorial board’s opinion.

 

How to Cite

Pharmacological adherence to oral anticoagulant and factors that influence the international normalized ratio stability . (2011). Revista Latino-Americana De Enfermagem, 19(1), 18-25. https://doi.org/10.1590/S0104-11692011000100004