Abordagens terapêuticas do Condiloma Acuminado em crianças e adolescentes
DOI:
https://doi.org/10.11606/issn.2176-7262.rmrp.2022.195167Palavras-chave:
Condiloma Acuminado, Infecções por Papillomavirus, ImiquimodeResumo
Objetivos: A infecção pelo papiloma vírus humano dos tipos 6 e 11 pode evoluir para Condiloma Acuminado. Sua transmissão é principalmente via sexual, de forma que a presença dessas verrugas em crianças deve ser considerada sinal de alarme para investigação de abuso. Eventualmente, contudo, ocorre por autoinoculação ou fômites. O tratamento é desafiador, dado que apesar do extenso arsenal, a recorrência se faz comum. A presente revisão sistemática advém a comparar taxas de sucesso das estratégias terapêuticas, objetivando fornecer substrato para escolha acertada no tratamento da doença em crianças e adolescentes. Métodos: Foi realizada Revisão sistemática baseada no guideline Preferred Report Items for Systematic Reviews and Meta-Analyses (PRISMA), registrada na Plataforma PROSPERO sob identificação CRD42021262090. Resultados: 211 estudos foram encontrados nas databases consultadas, de forma que 30 atenderam as propostas de critérios estabelecidos na pesquisa sistematizada. Esses passaram extração de dados para síntese qualitativa, demonstrando eficácia de métodos não-invasivos a invasivos. Conclusões: Mediante bons resultados em resolução da doença e reduzidos efeitos adversos, a terapia mais popular entre os autores foi o Imiquimode. A pesquisa chamou atenção à necessidade de estudos mais robustos e metodologias mais complexas a cerca das abordagens terapêuticas do Condiloma Acuminado em crianças e adolescentes.
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Copyright (c) 2022 Denise Gasparetti Drumond, Bárbara Bizzo Castelo, Samuel Drumond Esperança, Fellipe Bruno Dominiquini, Neila Maria de Góis Speck
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
