O Impacto do desequilíbrio da microbiota intestinal no desenvolvimento da obesidade
DOI:
https://doi.org/10.11606/issn.2176-7262.rmrp.2023.204198Palavras-chave:
Disbiose, Obesidade, Microbiota gastrointestinalResumo
OBJETIVO: revisar as bases de dados atuais para identificar os impactos da disbiose intestinal na obesidade, bem como servir de pilar para realização de medidas preventivas, diagnósticas e terapêuticas. METODOLOGIA: trata-se de revisão integrativa realizada a partir de coleta de dados obtidos nas plataformas SciELO, PubMed, BVS e LILACS usando os descritores “dysbiosis”, “obesity” and “gastrointestinal microbiome”; os critérios de inclusão foram: artigos publicados nos últimos 5 anos (de 2017 a 2022), artigos originais, metanálises e estudos observacionais (ensaios clínicos e estudo de coorte) e escritos em português, inglês ou espanhol. RESULTADOS: dieta ocidental e uso de adoçante provocam alterações antropométricas, de pressão arterial, intolerância à glicose, entre outras, além de levar à prevalência de bactérias deletérias ao organismo, culminando em obesidade e diabetes mellitus; em contrapartida, dieta rica em fibras e administração de probióticos podem gerar mudanças benéficas na diversidade da flora intestinal, ademais combatem o estado inflamatório gerado pela obesidade.
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Copyright (c) 2023 Anna Laura Gomes Goulart, Ester Maria de Almeida Costa, Mariana Guedes Lopes Bacelar, Sâmya Silveira Nascimento, Thaynara Faria Gomes
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
