Diferença de gênero no estresse oxidativo no sobrepeso e na obesidade em crianças e adolescentes
DOI:
https://doi.org/10.11606/issn.2176-7262.rmrp.2025.223754Palavras-chave:
Obesidade infantil, Sobrepeso infantil, Estresse oxidativoResumo
Objetivo: investigar a diferença entre gêneros nos parâmetros de estresse oxidativo em crianças e adolescentes com obesidade. Métodos: foi realizada uma revisão sistemática seguindo a diretriz PRISMA. As bases de dados Medline/PubMed, Web of Science, Embase e LILACS foram utilizadas. A análise do risco de viés foi realizada utilizando a escala Newcastle Ottawa (NOS). O estudo foi registrado na PROSPERO (CRD42023411205). Resultados: após aplicação de todos os critérios de inclusão e exclusão este estudo selecionou 7 artigos para avaliação dos biomarcadores de estresse oxidativo. Observamos que a condição de obesidade na infância e adolescência está relacionada ao estresse oxidativo e aos processos inflamatórios, e a resposta antioxidante pode ser dependente do grau de obesidade e do sexo. Conclusão: Os resultados sugerem que a condição de obesidade na infância e na adolescência está relacionada ao estresse oxidativo e aos processos inflamatórios sendo mais evidente com maior grau de obesidade. Além disso, estudos indicam que meninas com obesidade apresentam maior capacidade antioxidante em comparação aos meninos em condição semelhante de obesidade. No entanto, destacamos a falta de resultados conclusivos pela escassez de estudos que investigaram a comparação de gênero considerando diferenças hormonais, níveis de atividade física e padrões culturais para fornecer uma compreensão mais sólida e abrangente desta complexa questão.
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Copyright (c) 2025 Thyago de Oliveira Rodrigues, Thaynan Raquel dos Prazeres Oliveira, Jonata Henrique Santana, Aline Isabel Silva, Samarjit Das, Claudia Jacques Lagranha
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
