The challenge of therapeutical management of primary pleural epithelioid hemangioendothelioma
case report
DOI:
https://doi.org/10.11606/issn.2176-7262.v52i4p349-354Keywords:
Epithelioid, Hemangioendothelioma, Pleura, ThoraxAbstract
Epithelioid hemangioendothelioma (EH) is a rare malignant tumor of vascular endothelial origin that can affect several tissues. Among its various possible clinical presentations, primary pleural EH (PPEH) is a rarely reported subtype with aggressive, unpredictable behavior, poor prognosis, and low survival. We report a case of PPEH in a 51-year-old male who presented with chest and abdominal pain, shortness of breath, and weight loss. The diagnosis of PPEH was confirmed by histopathology and immunohistochemistry. After 5 cycles of chemotherapy with carboplatin and paclitaxel, the patient achieved improvement of symptoms with stable disease, however, he remained alive for 10 months after diagnosis. Given the rarity of PPEH, there is little data to guide its management. Further studies are needed to develop effective therapeutic strategies and improve patient survival.
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