Spirometry and impulse oscillometry during acute pulmonary exacerbation hospitalization in children with cystic fibrosis
DOI:
https://doi.org/10.11606/issn.2176-7262.rmrp.2022.183755Keywords:
Cystic Fibrosis, Symptom Flare Up, Respiratory Function Tests, Respiratory MechanicsAbstract
Objective: Evaluate the respiratory system parameters of children with cystic fibrosis (CF) during hospitalization for acute pulmonary exacerbation (APE) treatment. Methods: observational study before-after that occurred at the CF reference center. There were included children with cystic fibrosis (CF) between six to 15 years old hospitalized due to APE. The registration of the APE clinical scores, anthropometric data, and respiratory system (IOS and spirometry) evaluation occurred at the beginning (T1), during (T2), and at the end (T3) of the hospitalization. There were registered pathogens, genetic mutation, disease severity (Schwachman-Doershuk Score), and the most recent spirometry when they were clinically stable. The Shapiro-Wilk test was applied to analyze data distribution, and the repeated measure ANOVA, Friedman test, Tpaired test, and Wilcoxon test were performed to compare data, with a significance level set at 5%. Results: sixteen children/adolescents participated in the study (68.8% girls, 12.88±1.67 years old). The spirometric parameters, X5 parameter, and anthropometric data increased (p<0.005) and the APE scores decreased (p<0.005) at T3. Conclusion: APE scores, anthropometric data, spirometric parameters, and IOS elastic recoil parameter (X5) at the end of hospitalization.
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Copyright (c) 2022 Tayná Castilho, Renata Wamosy, Camila Schivinski
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