Benzodiazepines utilization in Brazilian older adults: a population-based study
DOI:
https://doi.org/10.11606/s1518-8787.2022056003740Keywords:
Aged, Drug Utilization, Benzodiazepines, Risk Factors, Cross-Sectional StudiesAbstract
OBJECTIVE: To evaluate the utilization of benzodiazepines (BZD) in Brazilian older adults, based on the Pesquisa Nacional de Acesso, Utilização e Promoção do Uso Racional de Medicamentos (PNAUM - National Survey of Access, Use and Promotion of Rational Use of Medicines). METHODS: The PNAUM is a cross-sectional study conducted between 2013 and 2014, representing the Brazilian urban population. In the present study, we included 60 years or older (n = 9019) individuals. We calculated the prevalence of BZD utilization in the 15 days prior to survey data collection according to independent variables, using a hierarchical Poisson regression model. A semistructured interview performed empirical data collection (household interview). RESULTS: The prevalence of BZD utilization in the older adults was 9.3% (95%CI: 8.3–10.4). After adjustments, BZD utilization was associated with female sex (PR = 1.88; 95%CI: 1.52–2.32), depression (PR = 5.31; 95%CI: 4.41–6, 38), multimorbidity (PR = 1.44; 95%CI: 1.20–1.73), emergency room visit or hospitalization in the last 12 months (PR = 1.42; 95%CI: 1.18–1.70 ), polypharmacy (PR = 1.26; 95%CI: 1.01–1.57) and poor or very poor self-rated health (PR = 4.16; 95%CI: 2.10–8.22). Utilization was lower in the North region (PR = 0.18; 95%CI: 0.13–0.27) and in individuals who reported abusive alcohol consumption in the last month (PR = 0.42; 95%CI: 0.19–0.94). CONCLUSION: Despite contraindications, results showed a high prevalence of BZD utilization in older adults, particularly in those with depression, and wide regional and sex differences.
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Copyright (c) 2022 Marina de Borba Oliveira Freire, Bruna Gonçalves Cordeiro da, Andréa Dâmaso Bertoldi, Andréia Turmina Fontanella, Sotero Serrate Mengue, Luiz Roberto Ramos, Noemia Urruth Leão Tavares, Tatiane da Silva Dal Pizzol, Paulo Sérgio Dourado Arrais, Mareni Rocha Farias, Vera Lucia Luiza, Maria Auxiliadora Oliveira, Ana Maria Baptista Menezes
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Ministério da Saúde
Grant numbers 25000.111834/2
