Dissatisfaction with SUS pharmaceutical services and nonadherence to medication use

Authors

  • Poliana Vieira da Silva Menolli Universidade Estadual do Oeste do Paraná. Centro de Ciências Médicas e Farmacêuticas. Programa de Pós-Graduação em Ciências Farmacêuticas. Cascavel, PR, Brasil https://orcid.org/0000-0001-9741-1049
  • Edmarlon Girotto Universidade Estadual de Londrina. Centro de Ciências da Saúde. Departamento de Ciências Farmacêuticas. Programa de Pós-graduação em Saúde Coletiva. Londrina, PR, Brasil https://orcid.org/0000-0001-9345-3348

DOI:

https://doi.org/10.11606/s15188787.2025059006463

Keywords:

Patient satisfaction, Pharmaceutical Services, Medication Adherence, Chronic Disease, Primary Health Care

Abstract

OBJECTIVE: To analyze the association between user dissatisfaction with the pharmaceutical services provided by the Brazilian Unified Health System (SUS) and nonadherence to medication use by patients with chronic non-communicable diseases. Correspondence: Poliana Vieira da Silva Menolli  Universidade Estadual do Oeste do Paraná  Centro de Ciências Médicas e Farmacêuticas Rua Universitária, 1.619  85819-110 Cascavel, PR, Brazil Email: poliana.menolli@unioeste.br Received: Jul 9, 2024 Approved: Feb 25, 2025 How to cite: Menolli PVS, Girotto E. Dissatisfaction with SUS pharmaceutical services and nonadherence to medication use. Rev. Saude Publica. 2025;59:e36. https://doi.org/10.11606/s15188787.2025059006463 Associate Editor:  Paulo Frazão Copyright: This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided that the original author and source are credited. METHODS: A cross-sectional study with data from the service evaluation component  of the Pesquisa Nacional sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos in Brazil, conducted from July to December 2014. In-person interviews were analyzed with SUS users aged 18 or over who had used medications for hypertension, diabetes, and dyslipidemia and had visited SUS pharmacies in the three months prior to the survey. The dependent variable was medication nonadherence, assessed through three measures: nonadherence due to lack of medication, nonadherence in the past seven days and declared nonadherence. The independent variable was dissatisfaction with the dimensions of pharmaceutical services (timeliness, availability, and accommodation), measured using item response theory. Logistic regression was performed to calculate crude and adjusted odds ratios (OR).  RESULTS: A total of 2,448 users were evaluated. Nonadherence due to lack of medication was 31.6%; in the past seven days was 11.5%; and declared nonadherence 13.0%. Lack of access and forgetfulness were the main reasons for nonadherence in the past seven days. In the adjusted analysis, dissatisfaction with the “timeliness” dimension was associated with nonadherence in the past seven days (OR = 1.489; 95%CI: 1.023–2.168) and the “accommodation” dimension was associated with declared nonadherence (OR = 3.132; 95%CI: 2.266–4.329). CONCLUSION: Dissatisfied users were more likely to be nonadherent to medication use across all service dimensions, and dissatisfaction with the availability and accommodation of pharmaceutical services was associated with nonadherence.

References

Batbaatar E, Dorjdagva J, Luvsannyam A, Savino MM, Amenta P. Determinants of patient satisfaction: a systematic review. Perspect Public Health. 2017 mar;137(2):89–101. https://doi.org/10.1177/1757913916634136

Huyard C, Derijks L, Haak H, Lieverse L. Intentional Nonadherence as a means to exert control. Qual Health Res. 2017 jul;27(8):1215–24. https://doi.org/10.1177/1049732316688882

World Health Organization. Adherence to long term therapies: evidence for action. Geneva: WHO; 2003.

Ferreira DC, Vieira I, Pedro MI, Caldas P, Varela M. Patient satisfaction with healthcare services and the techniques used for its assessment: a systematic literature review and a bibliometric analysis. Healthcare (Switzerland). 2023 fev;11(5):639. https://doi.org/10.3390/healthcare11050639.

Esperidião MA, Viera-da-Silva LM. A satisfação do usuário na avaliação de serviços de saúde: ensaio sobre a imposição de problemática. Saúde Debate. 2018 out;42(spe2):331–40. https://doi.org/10.1590/S0102-311X2006000600016

Gouveia GC, Souza WV de, Luna CF, Souza-Júnior PRB, de Szwarcwald CL. Satisfação dos usuários do sistema de saúde brasileiro: fatores associados e diferenças regionais. Rev Bras Epidemiol. 2009 set;12(3):281–96. https://doi.org/10.1590/S1415-790X2009000300001

Donabedian, A. Evaluating the quality of medical care. Milbank Quarterly. 2005 dez;83(4):691–729. https://doi.org/10.1111/j.1468-0009.2005.00397.x

Esperidião M, Trad LAB. Avaliação de satisfação de usuários. Ciênc Saúde Colet. 2005 dez;10(suppl):303–12. https://doi.org/10.1590/S1413-81232005000500031

Ministério da Saúde (BR). Cuidado farmacêutico na atenção básica. Caderno 1: Serviços farmacêuticos na atenção básica à saúde. Brasília, DF: Ministério da Saúde; 2014.

Ministério da Saúde (BR). Diretrizes nacionais do cuidado farmacêutico no âmbito do Sistema Único de Saúde – SUS. Brasília, DF: Ministério da Saúde; 2024.

Esher Â, Santos EM, Magarinos-Torres R, Azeredo TB. [Building evaluation criteria: experts and user satisfaction with pharmaceutical delivery services for HIV/Aids]. Ciênc Saúde Colet. 2012 jan;17(1):203–14. https://doi.org/10.1590/s1413-81232012000100022

Soeiro OM, Tavares NUL, Nascimento Júnior JM, Guerra Junior AA, Costa EA, Acurcio FA, et al. Patient satisfaction with pharmaceutical services in Brazilian primary health care. Rev Saude Publica. 2017 set;51(suppl.2):21s. https://doi.org/10.11606/S1518-8787.2017051007145

Hugtenburg JG, Vervloet M, Van Dijk L, Timmers E. Definitions, variants, and causes of nonadherence with medication: a challenge for tailored interventions. Patient Pref Adherence. 2013 jul;7(1):675–82. https://doi.org/10.2147/PPA.S29549

Gellad WF, Thorpe CT, Steiner JF, Voils CI. The myths of medication adherence. Pharmacoepidemiol Drug Saf. 2017 dez;26(12):1437–41. https://doi.org/10.1002/pds.4334

Raebel MA, Schmittdiel J, Karter AJ, Konieczny JI, Steiner JF. Standardizing terminology and definitions of medication adherence and persistence in research employing electronic databases. Med Care. 2013 ago;51(8 suppl 3):S11–S21. https://doi.org/10.1097/MLR.0b013e31829b1d2a

Santa-Helena E, Nemes MIB, Eluf Neto J. Fatores associados à não-adesão ao tratamento com anti-hipertensivos em pessoas atendidas em unidades de saúde da família. Cad Saude Publica. 2010 dez;26(12):2389–98. https://doi.org/10.1590/S0102-311X2010001200017

Barreto MS, Ganassin GS, Matsuda LM, Marcon SS. Dissatisfaction with the health service and non-adherence to antihypertensive medication treatment in Brazil*. Open J Nurs. 2015;5(1):49–57. https://doi.org/10.4236/ojn.2015.51006

Leon C, Koosed T, Philibert B, Raposo C, Benzaken AS. HIV/AIDS health services in Manaus, Brazil: Patient perception of quality and its influence on adherence to antiretroviral treatment. BMC Health Serv Res. 2019 maio;19(1):344. https://doi.org/10.1186/s12913-019-4062-9

Álvares J, Alves MCGP, Escuder MML, Almeida AM, Izidoro JB, Guerra Junior AA, et al. National Survey on Access, Use and Promotion of Rational Use of Medicines: methods. Rev Saude Publica. 2017 nov;51(suppl.2):1s–9s. https://doi.org/10.11606/S1518-8787.2017051007027

von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP. The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. Int J Surg. 2014 dez;12(12):1500-24. https://doi.org/ 10.1016/S0140-6736(07)61602-X

World Health Organization. ATC/DDT Index 2019. Geneva: WHO; 2019.

Sackett DL, Haynes RB, Gibson ES, Hackett BC, Taylor DW, Roberts RS, et al. Randomised clinical trial of strategies for improving medication compliance in primary hypertension. Lancet. 1975 maio;1(7918):1205-7. https://doi.org/10.1016/s0140-6736(75)92192-3

Rizopoulos D. ltm: an R Package for latent variable modeling and item response theory analyses. J Stat Softw. 2006;17(5):1–25. https://doi.org/10.18637/jss.v017.i05

Gast A, Mathes T. Medication adherence influencing factors—an (updated) overview of systematic reviews. Systematic Reviews. 2019 maio;8(1):112. https://doi.org/10.1186/s13643-019-1014-8

Gomes MAV, Pinto VO, Cassuce FCC. Determinants of satisfaction with the care provided by Basic Health Units (BHU). Ciênc Saúde Colet. 2021 abr;26(4):1311–22. https://doi.org/10.1590/1413-81232021264.18022019.

Protasio APL, Gomes LB, Machado LS, Valença AMG. Factors associated with user satisfaction regarding treatment offered in Brazilian primary health care. Cad Saude Publica. 2017 mar;33(2):1–15. https://doi.org/10.1590/0102-311x00184715

Fernandez-Lazaro CI, Adams DP, Fernandez-Lazaro D, Garcia-González JM, Caballero-Garcia A, Miron-Canelo JA. Medication adherence and barriers among low-income, uninsured patients with multiple chronic conditions. Res Social Adm Pharm. 2019 jun;15(6):744–53. https://doi.org/10.1016/j.sapharm.2018.09.006

Remondi FA, Cabrera MAS, Souza RKT. Não adesão ao tratamento medicamentoso contínuo: prevalência e determinantes em adultos de 40 anos e mais. Cad Saude Publica. 2014 jan;30(1):126–36. https://doi.org/10.1590/0102-311X00092613

Tavares NUL, Bertoldi AD, Mengue SS, Arrais PSD, Luiza VL, Oliveira MA, et al. Factors associated with low adherence to medicine treatment for chronic diseases in Brazil. Rev Saude Publica. 2016 dez;50(suppl 2):1–11. https://doi.org/10.1590/s1518-8787.2016050006150

Instituto Brasileiro de Geografia e Estatistica (BR). Pesquisa Nacional de Saúde 2019: informações sobre domicílios, acesso e utilização dos serviços de saúde. Brasília, DF: IBGE; 2020.

Instituto de Pesquisa Econômica Aplicada. Contas de Saúde na perspectiva da contabilidade Internacional 2015-2019. Brasília, DF: Ipea; 2022.

Linsky A, Simon SR, Bokhour B. Patient perceptions of proactive medication discontinuation. Patient Educ Couns. 2015 fev;98(2):220–5. https://doi.org/10.1016/j.pec.2014.11.010

Lycett H, Wildman E, Raebel EM, Sherlock JP, Kenny T, Chan AHY. Treatment perceptions in patients with asthma: Synthesis of factors influencing adherence. Respir Med. 2018 aug;141:180–9. https://doi.org/10.1016/j.rmed.2018.06.032

Lihara N, Nishio T, Okura M, Anzai H, Kagawa M, Houchi H, et al. Comparing patient dissatisfaction and rational judgment in intentional medication non-adherence versus unintentional non-adherence. J Clin Pharm Ther. 2014 fev;39(1):45–52. https://doi.org/10.1111/jcpt.12100

Temeloglu SE, Sertel Berk HO, Rezvani A. Serial mediation of illness perception and beliefs about medicines in the relationship between patient satisfaction and medication adherence: An evaluation of self-regulatory model in rheumatoid arthritis and ankylosing spondylitis patients. J Health Psychol. 2024 jul;29(8):836–47. https://doi.org/10.1177/13591053231213306

Carpenter CJ. A meta-analysis of the effectiveness of health belief model variables in predicting behavior. Health Commun. 2010 dez;25(8),661–9. https://doi.org/10.1080/10410236.2010.521906

Abu Khudair S, Khader YS, Morrissey H, El-Khatib Z, Sandor J. Fatores associados à adesão subótima a medicamentos hipertensos entre refugiados sírios – estudo transversal no campo de Zaatari, Jordânia. O Paciente Prefere Adesão. 2021 set;15:2125-2135. https://doi.org/10.2147/PPA.S327903

Jones CJ, Smith H, Llewellyn C. Evaluating the effectiveness of health belief model interventions in improving adherence: a systematic review, Health Psychol Rev. 2014;8(3):253–69. https://doi.org/10.1080/17437199.2013.802623

Olsen S, Smith SS, Oei TPS, Douglas J. Motivational interviewing (MINT) improves continuous positive airway pressure (CPAP) acceptance and adherence: a randomized controlled trial. J Consult Clin Psychol. 2012 fev;80(1):151–63. https://doi.org/10.1037/a0026302

Costa KS, Tavares NUL, Nascimento Júnior JM, Mengue SS, Álvares J, Guerra Junior AA, et al. Pharmaceutical services in the primary health care of the Brazilian Unified Health System: Rev Saude Publica. 2017 set;51:3s. https://doi.org/10.11606/S1518-8787.2017051007146

Leite SN, Bernardo NLMC, Álvares J, Guerra Junior AA, Costa EA, Acurcio FA, et al. Medicine dispensing service in primary health care of SUS. Rev Saude Publica. 2017 set;51:11s. https://doi.org/10.11606/S1518-8787.2017051007121

Pereira NC, Luiza VL, Campos MR, Chaves LA. Implementation of pharmaceutical services in Brazilian primary health care: a cross-sectional study. BMC Fam Pract. 2021 dez;22(1):170. https://doi.org/10.1186/s12875-021-01516-7

Bermudez JAZ, Esher A, Osorio-de-Castro CGS, Vasconcelos DMM, Chaves GC, Oliveira MA, et al. Assistência farmacêutica nos 30 anos do SUS na perspectiva da integralidade. Ciênc Saúde Colet. 2018 jun;23(6):1937–49. https://doi.org/10.1590/1413-81232018236.09022018

Rodrigues PS, Cruz MS, Tavares NUL. Avaliação da implantação do Eixo Estrutura do Programa Nacional de Qualificação da Assistência Farmacêutica no SUS. Saúde Debate. 2017 mar;41(spe):192–208. https://doi.org/10.1590/0103-11042017s15

Ministério da Saúde (BR). Portaria GMMS n. 635. Incentivo financeiro federal de implantação, custeio e desempenho para as modalidades de equipes multiprofissionais na atenção primária à saúde. Brasília, DF: Ministério da Saúde; 2023.

Published

2025-11-13

Issue

Section

Original Articles

How to Cite

Vieira da Silva Menolli, P., & Girotto, E. (2025). Dissatisfaction with SUS pharmaceutical services and nonadherence to medication use. Revista De Saúde Pública, 59, 36. https://doi.org/10.11606/s15188787.2025059006463

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