Neuropatia diabética: fisiopatologia, clínica e eletroneuromiografia
DOI:
https://doi.org/10.11606/issn.2317-0190.v7i1a102254Palavras-chave:
Neuropatias Diabéticas, Eletrofisiologia, FisiopatologiaResumo
A neuropatia afeta a maioria dos diabéticos de longa evolução. Sua melhor compreensão é de fundamental importância na formação de um correto raciocínio clínico. As principais vias fisiopatológicas conhecidas, a apresentação clínica e os achados eletrofisiológicos são revisados por meio de pesquisa na MedLine e alguns dados pessoais são apresentados. O conhecimento da fisiopatologia, da clínica e da eletrofisiologia são essenciais para uma abordagem crítica e racional dessa heterogênea e complexa patologia.
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Currie CJ, Morgan CL, Peters JR. The epidemiology and cost of inpatient care for peripheral vascular diasease, infection neuropathy, and ulceration in diabetes. Diabetes Care. 1998;21:42-48.
Selby JV, Ray GT, Zhang D, Colby CJ. Excess costs of medical care for patients with diabetes in a managed care population. Diabetes Care. 1997;20:1396-1402.
Cabezas-Carrero J. The prevalence of clinical diabetic polineuropathy in Spain: a study in primary care and hospital clinic groups. Diabetologia. 1998;41:1263-1269.
Benbow SJ, Wallymahmed ME, MacFarlane IA. Diabetic peripheral neuropathy and quality of life. Q J Med. 1998;91:733-737.
Grenne DA, Sima AAF, Stevens MJ, Feldman EL, Lattimers A. Complications: neuropathy, pathogenetic considerations. Diabetes Care. 1992;15:1902-1925.
Boulton AJM, Gries FA, Jervell JA. Guidelines for the diagnosis and management of diabetic peripheral neuropathy. Diab Med. 1998;15:508-514.
Thomas PK, Tomlinson DR. Diabetic and hipoglicemic neuropathy. In: Dick PJ. Peripheral neuropathy. Philadelphia: Saunders; 1993. p. 1219-1250.
Ross MA. Neuropathies associated with diabetes. Med Clin North Am. 1993;77:111-124.
Dyck PJ, Kratz KM, Karnes MS. The prevalence by staged severity of various types of diabetic neuropathy, retinopathy, and nephropathy in a population-based cohort: the Rochester Diabetic Neuropathy study. Neurology. 1993;43:817-824.
American Diabetes Associations. American Academy Of Neurology. Report and recomendations of the Santo Antonio conference on diabetic neuropathy. Diabetes Care. 1988;11:592-596.
Sangiorgio L, Iemmolo R, Le Moli R. Diabetic neuropathy: prevalence, concordance between clinical and electrophysiological testing and impact of risk factors. Panminerva Med. 1997;39:1-5.
Partanen J, Niskanen L, Lehtinen J. Natural history of peripheral neuropathy in patients with non-insulindependent diabetes mellitus. New Eng J Med. 1995;333:89-94.
Dyck PJ, Karnes JL, Daube J. Clinical and neuropathological criteria for the diagnosis and staging of the diabetic polyneuropathy. Brain. 1985;108:861-880.
Ishii DN. Implications of insulin-like growth factors in pathogenesis of diabetic neuropathy. Brain Research Reviews. 1995;20:47-67.
Giugliano D, Ciriello A, Paolisso G. Oxidative stress and diabetic vascular complications. Diabetes Care. 1996;19:257-267.
Sima AAF, Brismar T. Reversible diabetic nerve disfunction: structural correlates to electrophysiological abnormalities. Ann Neurol. 1985;18:21-29.
Brismar T, Sima AAF, Grenne DA. Reversible and irreversible nodal disfunction in diabetic neuropathy. Ann Neurol. 1987;21:504-507.
Dumitru D. Generalized peripheral neuropathies. In: Dumitru D. Electrodiagnostic medicine. Philadelphia: Hanley & Belfus; 1995. p. 741-850.
Schmidt RE, Dorsey DA, Beaudet LN. Effect of sorbitol dehydrogenase inhibition on experimental diabetic autonomic neuropathy. J Neuropathol Exp Neurol. 1998;57:1175-1189.
Low PA. Recent advances in the pathogenesis of diabetic neuropathy. Muscle Nerve. 1987;10:121-128.
Diemel LT, Cai F, Anand P. Increased nerve growth factor mRNA in lateral calf skin biopsies from diabetic patients. Diad Med. 1999;16:113-118.
Elias KA, Cronin MJ, Stewart TA. Peripheral neuropathy in transgenic diabetic mice. Diabetes. 1998;47:1637-1642.
Apfel SC, Kessler JA, Adornato BT. Recombinant human nerve growth factor in the treatment of diabetic polyneuropathy. Neurology. 1998;51:695-702.
Krendel DA, Costigan DA, Hopkins LC. Successful treatment of neuropathies in patients with diabetes mellitus. Arch Neurol. 1995;52:1053-1061.
Stewart JD, McKelvey R, Durcan L. Chronic inflamatory demyelinating polyneuropathy (CIDP) in diabetics. J Neurol Science. 1996;142:59-64.
Low PA. Autonomic neuropathies. Curr Opin Neurol. 1998;11:531-537.
Vinik AI. Diagnosis and management of diabetic neuropathy. Clinics in Geriatric Medicine. 1999;51:293-321.
Andersen H, Stalberg E, Gjerstad MD, Jakobsen J. Association of muscle strength and electrophysiological measures of reinnervation in diabetic neuropathy. Muscle Nerve. 1998;21:1647-1654.
Pfeifer MA, Ross DR, Schrage JP. A highly successful and novel model for treatment of chronic painful diabetic peripheral neuropathy. Diabetes Care. 1993;16:1103-1115.
Kong MA, Horowitz M, Dipappsci KLJ, Harding PE. Natural history of diabetic gastroparesis. Diabetes Care. 1999;22:503-507.
Ducher M, Cerutti C, Gustin MD. Noninvasive exploration of cardiac autonomic neuropathy. Diabetes Care. 1999;22:388-393.
Ewing DJ, Martyn CN, Yong RJ, Clarce BF. The value of cardiovascular autonomic function tests: 10 years of experience in diabetes. Diabetes Care. 1985;8:494-498.
Jermend J, Davidovits Z, Khoor S. Silent coronary artery disease in diabetic patients with cardiac autonomic neuropathy. Diabetes Care. 1994;17:1231-1232.
Rathman W, Ziegler D, Jahnke M. Mortality in diabetic patients with cardivascular autonomic neuropathy. Diabet Med. 1993;10:820-824.
Watanabe K, Hagura R, Akamura Y. Characteristics of cranial nerve palsies in diabetic patients. Diad Res Clin Pract. 1990;10:19-27.
Urban PP, Forst T, Lenfers M. Incidence of subclinical trigeminal and facial involvement in diabetes mellitus. Electromyogr Clin Neurophysiol. 1999;39:267-272.
Quasthoff S. The role of axonal ion conductances in diabetic neuropathy: a review. Muscle Nerve. 1998;21:1246-1255.
Wilson JR, Stittsworth JD, Kadir A, Fisher MA. Conduction velocity versus amplitude analysis: evidence for demyelination in diabetic neuropathy. Muscle Nerve. 1998;21:1228-1230.
Kraft GH. Peripheral neuropathies. In: Johnson EW. Practical electromyography. Baltimore: Williams & Wilkins; 1988. p. 246-318.
DeLisa JA, Lee HJ, Baran EM, Lai KS, Spielholz N. Manual of nerve conduction velocity and clinical neurophysiology. 3rd ed. New York: Raven Press; 1994. p. 144-145.
Andersen H, Stalberg E, Falck B. F-wave latency, the most sensitive nerve conduction parameter in patients with diabetes mellitus. Muscle Nerve. 1997;20:1296-1302.
Falck B, Stalberg E, Bischoff C. Sensory nerve conduction studies with surface electrodes. Methods Clin Neurophysiol. 1994;5:1-20.
Stalberg E, Falck B. Clinical motor nerve conduction studies. Methods Clin Neurophysiol. 1993;4:61-80.
Toyokura M, Ishida A. Clinical significance of the F-wave area in diabetic polyneuropathy. Electromyogr Clin Neurophysiol. 1999;39:93-99.
Bril V, Ellison R, Ngo M. Electrophysiological monitoring in clinical trials. Muscle Nerve. 1998;21:1368-1373.
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