Papel do Plasma rico em plaquetas no manejo da dor

Autores

  • Carlos Antonio da Costa Junior Universidade Federal do Pará. Centro Integrado de Inclusão e Reabilitação
  • Wellington Luiz Fagundes Braun Clínica Plenus

DOI:

https://doi.org/10.11606/issn.2317-0190.v31iSupl.1a225097

Palavras-chave:

Plasma Rico em Plaquetas, Dor, Medicina Regenerativa, Peptídeos e Proteínas de Sinalização Intercelular, Plaquetas

Resumo

Plasma rico em plaquetas (PRP) é um concentrado autólogo de plaquetas derivado de sangue do próprio paciente (Carr et al.). Na resposta orgânica à lesão, dá-se início a um processo regenerativo como resposta ao dano tecidual, auxiliado principalmente por plaquetas (Chiavaras et al.).

Downloads

Os dados de download ainda não estão disponíveis.

Referências

Agarwal V, Gupta A, Singh H, Kamboj M, Popli H, Saroha S. Comparative Efficacy of Platelet-Rich Plasma and Dry Needling for Management of Trigger Points in Masseter Muscle in Myofascial Pain Syndrome Patients: A Randomized Controlled Trial. J Oral Facial Pain Headache. 2022;36(3-4):253–262. Doi: https://doi.org/10.11607/ofph.3188

Ahmed YE, Ahmed GM, Ghoneim AG. Evaluation of postoperative pain and healing following regenerative endodontics using platelet-rich plasma versus conventional endodontic treatment in necrotic mature mandibular molars with chronic periapical periodontitis. A randomized clinical trial. Int Endod J. 2023;56(4):404- 418. Doi: https://doi.org/10.1111/iej.13886

Al-Ajlouni J, Awidi A, Samara O, Al-Najar M, Tarwanah E, Saleh M, et al. Safety and Efficacy of Autologous Intra-articular Platelet Lysates in Early and Intermediate Knee Osteoarthrosis in Humans: A Prospective Open-Label Study. Clin J Sport Med. 2015;25(6):524-8. Doi: https://doi.org/10.1097/JSM.0000000000000166

Alsousou J, Keene DJ, Hulley PA, Harrison P, Wagland S, Byrne C, et al. Platelet rich Plasma in Achilles Tendon Healing 2 (PATH-2) trial: protocol for a multicentre, participant and assessor-blinded, parallel-group randomised clinical trial comparing platelet-rich plasma (PRP) injection versus placebo injection for Achilles tendon rupture. BMJ Open. 2017;7(11):e018135. Doi: https://doi.org/10.1136/bmjopen-2017-018135

Carr A, Cooper C, Murphy R, Watkins B, Wheway K, Rombach I, et al. PARot--assessing platelet-rich plasma plus arthroscopic subacromial decompression in the treatment of rotator cuff tendinopathy: study protocol for a randomized controlled trial. Trials. 2013;14:167. Doi: https://doi.org/10.1186/1745-6215-14-167

Chiavaras MM, Jacobson JA, Carlos R, Maida E, Bentley T, Simunovic N, et al. IMpact of Platelet Rich plasma OVer alternative therapies in patients with lateral Epicondylitis (IMPROVE): protocol for a multicenter randomized controlled study: a multicenter, randomized trial comparing autologous platelet-rich plasma, autologous whole blood, dry needle tendon fenestration, and physical therapy exercises alone on pain and quality of life in patients with lateral epicondylitis. Acad Radiol. 2014;21(9):1144-55. Doi: https://doi.org/10.1016/j.acra.2014.05.003

Christin IS, Muthukannan H, Karuppanan S, Chhajed SS, Suggu SR, Moitra S. Clinical use of Plasma Protein from Platelet in Degenerative Joint Disease: A Prospective Study. J Orthop Case Rep. 2022;12(11):105-109. Doi: https://doi.org/10.13107/jocr.2022.v12.i11.3434

Ding RY, Cheung GS, Chen J, Yin XZ, Wang QQ, Zhang CF. Pulp revascularization of immature teeth with apical periodontitis: a clinical study. J Endod. 2009;35(5):745-9. Doi: https://doi.org/10.1016/j.joen.2009.02.009

El-Sherif SM, Abdel-Hamid MM, Noureldin JMAM, Fahmy HM, Abdel-Naby HMA. Effectiveness of lyophilized growth factors injection for subacromial impingement syndrome: a prospective randomized double-blind placebo-controlled study. J Orthop Surg Res. 2023;18(1):78. Doi: https://doi.org/10.1186/s13018-023-03548-4

Hijazi A, Ahmed W, Gaafar S. Efficacy of intralesional injections of platelet-rich plasma in patients with oral lichen planus: A pilot randomized clinical trial. Clin Exp Dent Res. 2022;8(3):707-714. Doi: https://doi.org/10.1002/cre2.550

Kim SJ, Kim EK, Kim SJ, Song DH. Effects of bone marrow aspirate concentrate and platelet-rich plasma on patients with partial tear of the rotator cuff tendon. J Orthop Surg Res. 2018;13(1):1. Doi: https://doi.org/10.1186/s13018-017-0693-x

Laver L, Carmont MR, McConkey MO, Palmanovich E, Yaacobi E, Mann G, et al. Plasma rich in growth factors (PRGF) as a treatment for high ankle sprain in elite athletes: a randomized control trial. Knee Surg Sports Traumatol Arthrosc. 2015;23(11):3383-92. Doi: https://doi.org/10.1007/s00167-014-3119-x

Lim W, Park SH, Kim B, Kang SW, Lee JW, Moon YL. Relationship of cytokine levels and clinical effect on platelet-rich plasmatreated lateral epicondylitis. J Orthop Res. 2018;36(3):913-920. Doi: https://doi.org/10.1002/jor.23714

Linnanmäki L, Kanto K, Karjalainen T, Leppänen OV, Lehtinen J. Platelet-rich Plasma or Autologous Blood Do Not Reduce Pain or Improve Function in Patients with Lateral Epicondylitis: A Randomized Controlled Trial. Clin Orthop Relat Res. 2020;478(8):1892-1900. Doi: https://doi.org/10.1097/CORR.0000000000001185

Martin JI, Atilano L, Merino J, Gonzalez I, Iglesias G, Areizaga L, et al. Platelet-rich plasma versus lidocaine as tenotomy adjuvants in people with elbow epicondylopathy: a randomized controlled trial. J Orthop Surg Res. 2019;14(1):109. Doi: https://doi.org/10.1186/s13018-019-1153-6.

Martin JI, Merino J, Atilano L, Areizaga LM, Gomez-Fernandez MC, Burgos-Alonso N, et al. Platelet-rich plasma (PRP) in chronic epicondylitis: study protocol for a randomized controlled trial. Trials. 2013;14:410. Doi: https://doi.org/10.1186/1745-6215-14-410

Narang I, Mittal N, Mishra N. A comparative evaluation of the blood clot, platelet-rich plasma, and platelet-rich fibrin in regeneration of necrotic immature permanent teeth: A clinical study. Contemp Clin Dent. 2015;6(1):63-8. Doi: https://doi.org/10.4103/0976-237X.149294

Rodas G, Soler-Rich R, Rius-Tarruella J, Alomar X, Balius R, Orozco L, et al. Effect of Autologous Expanded Bone Marrow Mesenchymal Stem Cells or Leukocyte-Poor Platelet-Rich Plasma in Chronic Patellar Tendinopathy (With Gap >3 mm): Preliminary Outcomes After 6 Months of a Double-Blind, Randomized, Prospective Study. Am J Sports Med. 2021;49(6):1492-1504. Doi: https://doi.org/10.1177/0363546521998725

Schwitzguebel AJ, Bogoev M, Nikolov V, Ichane F, Lädermann A. Tennis elbow, study protocol for a randomized clinical trial: needling with and without platelet-rich plasma after failure of up-to-date rehabilitation. J Orthop Surg Res. 2020;15(1):462. Doi: https://doi.org/10.1186/s13018-020-01998-8

Smith PA. Intra-articular Autologous Conditioned Plasma Injections Provide Safe and Efficacious Treatment for Knee Osteoarthritis: An FDA-Sanctioned, Randomized, Double-blind, Placebo-controlled Clinical Trial. Am J Sports Med. 2016;44(4):884-91. Doi: https://doi.org/10.1177/0363546515624678

Tschopp M, Pfirrmann CWA, Fucentese SF, Brunner F, Catanzaro S, Kühne N, et al. A Randomized Trial of Intra-articular Injection Therapy for Knee Osteoarthritis. Invest Radiol. 2023;58(5):355-362. Doi: https://doi.org/10.1097/RLI.0000000000000942

Wongjarupong A, Pairuchvej S, Laohapornsvan P, Kotheeranurak V, Jitpakdee K, Yeekian C, et al. "Platelet-Rich Plasma" epidural injection an emerging strategy in lumbar disc herniation: a Randomized Controlled Trial. BMC Musculoskelet Disord. 2023;24(1):335. Doi: https://doi.org/10.1186/s12891-023-06429-3

Zhang C, Wang J, Wang L, Xie Y, Sun F, Jiang W, et al. The effect of physiotherapy in rotator cuff injury patients with platelet-rich plasma: study protocol of a non-randomized controlled trial. BMC Musculoskelet Disord. 2021;22(1):292. Doi: https://doi.org/10.1186/s12891-021-04171-2

Downloads

Publicado

2024-04-30

Edição

Seção

Resumos Expandidos

Como Citar

1.
Costa Junior CA da, Braun WLF. Papel do Plasma rico em plaquetas no manejo da dor. Acta Fisiátr. [Internet]. 30º de abril de 2024 [citado 25º de dezembro de 2025];31(Supl.1):S67-S69. Disponível em: https://revistas.usp.br/actafisiatrica/article/view/225097