Thrombosis and amputation in acute COVID-19: a case report

Authors

  • Kleber Jessivaldo Gomes das Chagas Instituto de Medicina Física e Reabilitação do Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo
  • Nilson Faria Junior Faculdade de Medicina da Universidade de São Paulo
  • Iago Israel Faculdade de Medicina da Universidade de São Paulo
  • Thais de Souza Oewel Faculdade de Medicina da Universidade de São Paulo
  • André Tadeu Sugawara Instituto de Medicina Física e Reabilitação do Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo
  • Gerson Sobrinho Salvador de Oliveira Instituto de Medicina Física e Reabilitação do Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo
  • Marta Imamura Departamento de Medicina Legal, Bioética, Medicina do Trabalho e Medicina Física e Reabilitação, Faculdade de Medicina da Universidade de São Paulo
  • Linamara Rizzo Battistella Departamento de Medicina Legal, Bioética, Medicina do Trabalho e Medicina Física e Reabilitação, Faculdade de Medicina da Universidade de São Paulo

DOI:

https://doi.org/10.11606/issn.2317-0190.v31i2a214105

Keywords:

Covid-19, Amputees, Thrombosis, Rehabilitation

Abstract

During the outbreak of COVID-19, it has been discovered that the infection was associated to increased risk of venous or arterial thromboembolic events and many other dysfunctions in various systems of human body. In relation to thrombosis, in molecular/cellular levels numerous signaling pathways due to dysregulated RAAS may contribute to the observed coagulopathy in COVID-19. On the other hand, excessive innate immune response to SARS-CoV2 for which there is no prior acquired immunity mediates various pathways that may lead to thrombosis. Case report: This case report analyzes those hematologic disfunctions in a patient affected for a post COVID-19 conditions associated to a long-term hospitalization resulting in a bunch of sequels. We emphasized the transfemoral amputation was due to proximal arterial thrombosis and the functional loss related to it. We aborted the whole rehabilitation plan and its implementation since the beginning of the process of dehospitalization. We describe the role of each professional of the multi-professional team, the pharmacologic and non-pharmacologic treatment, the assistive technologies applied, the other sequels related to post COVID-19 conditions and long-term hospitalization and their functional gains. We used the Functional Independence Measure (MIF) to do the follow up of the case, 84 to 96. As results of the therapeutic program, the patient could achieve a high grade of modified independence for activities of daily living (ADLS) and Instrumental activities of daily living. Conclusion: Thrombosis and amputations are complications in COVID-19 patients. The absence of a multidisciplinary program of rehabilitation will cause to the patient an increasing risk of development of psychologic affections and great impact of their social life.

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References

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Published

2024-06-28

Issue

Section

Case Report

How to Cite

1.
Chagas KJG das, Faria Junior N, Israel I, Oewel T de S, Sugawara AT, Oliveira GSS de, et al. Thrombosis and amputation in acute COVID-19: a case report. Acta Fisiátr. [Internet]. 2024 Jun. 28 [cited 2024 Nov. 21];31(2):121-4. Available from: https://revistas.usp.br/actafisiatrica/article/view/214105