Enterococcus faecalis causes osteitis deformans in a Golden Lancehead snake (Bothrops insularis): a case report

Viviane Campos Garcia; Pedro Enrique Navas-Suárez; Ana Carolina Brandão de Campos Fonseca-Pinto; Silvana Maria Unruh; Terezinha Knöbl; Mirian Halásc Vac; Claudia Momo; Maria Alejandra Arias Lugo; José Luiz Catão-Dias; Selma Maria Almeida-Santos

doi:10.11606/issn.1678-4456.bjvras.2020.163926

Authors

Viviane Campos Garcia Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia - Anatomia dos Animais Domésticos e Silvestres https://orcid.org/0000-0002-7605-8300
Pedro Enrique Navas-Suárez Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Patologia Experimental e Comparada https://orcid.org/0000-0003-1385-901X
Ana Carolina Brandão de Campos Fonseca-Pinto Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Clínica Cirúrgica Veterinária - Diagnóstico por Imagem https://orcid.org/0000-0003-2833-2069
Silvana Maria Unruh Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Clínica Cirúrgica Veterinária - Diagnóstico por Imagem https://orcid.org/0000-0002-3404-8286
Terezinha Knöbl Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Patologia Experimental e Comparada https://orcid.org/0000-0001-7107-5710
Mirian Halásc Vac Instituto Butantan, Laboratório de Ecologia e Evolução https://orcid.org/0000-0002-2605-5830
Claudia Momo Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Patologia Experimental e Comparada https://orcid.org/0000-0001-7265-9152
Maria Alejandra Arias Lugo Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Patologia Experimental e Comparada https://orcid.org/0000-0001-8219-8222
José Luiz Catão-Dias Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Patologia Experimental e Comparada https://orcid.org/0000-0003-2999-3395
Selma Maria Almeida-Santos Instituto Butantan, Laboratório de Ecologia e Evolução https://orcid.org/0000-0002-3928-1183

DOI:

https://doi.org/10.11606/issn.1678-4456.bjvras.2020.163926

Keywords:

Reptiles, Bone pathology, Paralysis, Captive breeding, Proliferative bone diseases

Abstract

Osteitis deformans (Paget’s disease) is a chronic bone disorder characterized by excessive osteoclast-mediated bone resorption followed by new bone formation. The present paper reports this condition in an 18-year-old captive golden lancehead (Bothrops insularis) from Brazil. This patient initially exhibited anorexia and swelling in the middle third of the spine associated with locomotor disability. For diagnosis, radiography, ultrasound, computed tomography, cytology, and microbiological culture were performed. Diagnostic imaging showed bone changes, vertebral fusion, and bone proliferation. Cytology revealed blood cells how toxic heterophiles, reactive monocytes, young red blood cells, and polychromasia compatible with an infectious process. A bacterial culture identified an ampicillin-susceptible strain of Enterococcus faecalis. Antibiotic treatment was promptly started, but the snake died 25 days later. Histopathologically, the bone tissue showed a generalized thickening of the vertebral trabeculae. For the first time, the presence of E. faecalis associated with the development of osteitis deformans in snakes was presented.

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Enterococcus faecalis causes osteitis deformans in a Golden Lancehead snake (Bothrops insularis): a case report

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