Use of the synthetic adhesive enbucrilate (Hystoacril®) in the repair of deep corneal ulcers: experimental study in dogs (Canis familiaris, Linnaeus, 1758)

Abstract

This study consisted in the application of a synthetic adhesive in corneas prepared on trials of size and deepness standard superficial keratectomies. Twenty one dogs were used, whose corneas received the adhesive in study. The animals were divided in 6 experimental groups and one control group, each one with three animals, which were followed up by different periods post-operative, as follow: 1; 3; 7; 15; 30 and 60 days. At the end of each period, the corneas were collected and kept in tamponade formalin. Clinical and histopathological evaluation showed inflammatory reaction to the synthetic adhesive as compared to the control group. The synthetic adhesive remained for 20 days. It was concluded that adhesives are useful for the repair of corneal lesions, as confirmed by the corneal tissue stability.