Histochemical comparative study of primary and metastatic tumors in nude rats xenotransplanted with KB cells

Authors

  • Terezinha Regina Prúpere Ogata Instituto Butantã, Laboratório de Anatomia Patológica, São Paulo, SP
  • José Luiz Guerra Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Patologia, São Paulo, SP
  • Francisco Javier Hernandez Universidade de São Paulo, Faculdade de Zootecnia e Engenharia de Alimentos, Pirassununga, SP

DOI:

https://doi.org/10.11606/issn.2318-3659.v34i4p203-206

Keywords:

Extracellular matrix, KB cells, Histochemical, Nude rats

Abstract

A comparative study of metastic and primitive tumors extra-celular matrix in nude rats, xenotransplanted with KB cells, using histochemical methods, was carried out. In both primitive and metastatic tumors it was possible to observe a qualitative and a quantitative variation of matricial components; coexistence of different kinds of fibers; small representation of elastic fibers; presence of acid and sulfated glycosaminoglycans and neutral polysacharyds, and also absence of basal membrane. It is suggested a small interaction between collagenic components and proteoglycan of primary tumors and the proteoglycan, whereas in métastasés this interaction is increased.

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Published

1997-08-01

Issue

Vol. 34 No. 4 (1997)

Section

BASIC SCIENCES

License

The journal content is authorized under the Creative Commons  BY-NC-SA  license (summary of the license: https://creativecommons.org/licenses/by-nc-sa/4.0 | full text of the license: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode) 

How to Cite

1.
Ogata TRP, Guerra JL, Hernandez FJ. Histochemical comparative study of primary and metastatic tumors in nude rats xenotransplanted with KB cells. Braz. J. Vet. Res. Anim. Sci. [Internet]. 1997 Aug. 1 [cited 2025 Mar. 11];34(4):203-6. Available from: https://revistas.usp.br/bjvras/article/view/50294