The effect of Bach flower remedies on hope and quality of life in people with advanced cancer: a triple-blind randomized clinical trial

Authors

  • Leonel dos Santos Silva Universidade Federal do Paraná, Programa de Pós-Graduação em Enfermagem, Curitiba, PR, Brasil.
  • Amanda Gomes de Miranda Universidade Federal do Paraná, Programa de Pós-Graduação em Enfermagem, Curitiba, PR, Brasil.
  • Larissa Marcondes Universidade Federal do Paraná, Programa de Pós-Graduação em Enfermagem, Curitiba, PR, Brasil.
  • Ruth Natalia Teresa Turrini Universidade de São Paulo, Escola de Enfermagem, Departamento de Enfermagem Médico-Cirúrgica, São Paulo, SP, Brasil.
  • Paulo Ricardo Bittencourt Guimarães Universidade Federal do Paraná, Departamento de Estatística, Curitiba, PR, Brasil.
  • Maria de Fátima Mantovani Universidade Federal do Paraná, Programa de Pós-Graduação em Enfermagem, Curitiba, PR, Brasil.
  • Luciana de Alcantara Nogueira Universidade Federal do Paraná, Programa de Pós-Graduação em Enfermagem, Curitiba, PR, Brasil.
  • Luciana Puchalski Kalinke Universidade Federal do Paraná, Programa de Pós-Graduação em Enfermagem, Curitiba, PR, Brasil.

DOI:

https://doi.org/10.1590/1980-220X-REEUSP-2025-0451pt

Keywords:

Flower Essences, Hope, Quality of Life, Integrative Oncology, Palliative Care

Abstract

Objective: To evaluate the effect of Bach Flower Remedies Therapy on the hope and quality of life of people with advanced cancer. Method: Randomized, triple-blind (1:1) clinical trial in a high-complexity public hospital in the Southern region of Brazil. Ninety-nine participants were allocated to either the intervention group (solution with nine flower essences) or the placebo group (Hydro-brandy solution). Both groups used four drops orally, four times a day, for 120 days, with monthly follow-up. Hope measured by the Herth Hope Index, quality of life through Functional Assessment of Chronic Illness Therapy – Palliative Care. Results: In the flower remedies group (n = 50), hope varied from 43.44/48 to 44.53/48 and in the placebo group (n = 49) from 41.67/48 to 44.29/48, a significant increase over time (p = 0.024), with no difference between groups (p = 0.977). Quality of life ranged from 141.39/184 to 150.60/184 in the flower remedies group, and from 133.76/184 to 148.96/184 in the placebo group, with no significant difference between groups (p = 0.230) or time (p = 0.240). Conclusion: Although not statistically significant, there was a slight increase in life expectancy and quality of life, highlighting the importance of non-pharmacological therapies in evidence-based palliative care practice. Brazilian Registry of Clinical Trials: RBR-8q6z6kq.

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References

Published

2026-07-20

Issue

Section

Original Article

How to Cite

Silva, L. dos S., Miranda, A. G. de, Marcondes, L., Turrini, R. N. T., Guimarães, P. R. B., Mantovani, M. de F., Nogueira, L. de A., & Kalinke, L. P. (2026). The effect of Bach flower remedies on hope and quality of life in people with advanced cancer: a triple-blind randomized clinical trial. Revista Da Escola De Enfermagem Da USP, 60, e20250451. https://doi.org/10.1590/1980-220X-REEUSP-2025-0451pt