Behavior of glycemic variability in hospitalized type 2 Diabetes Mellitus patients
DOI:
https://doi.org/10.11606/issn.2176-7262.rmrp.2022.193922Keywords:
Glycemia, C-reactive protein, Nutritional therapyAbstract
Introduction: Hyperglycemia may be present in up to 38% of hospitalized patients. Glycemic control is associated with better clinical outcomes.Objective: to assess the behavior of glycemic variability in hospitalized patients with Diabetes Mellitus 2.Methodology: Cross-sectional study composed of hospitalized patients with and without diabetes, adults and elderly, of both genders, undergoing enteral nutritional therapy. Blood glucose was measured by capillary blood glucose tests and classified as normoglycemia, hyperglycemia and glycemic variability, assessed from the glycemic standard deviation and glycemic variation coefficient. Biochemical data such as C-reactive protein were assessed. Two-way analysis of variance (ANOVA) was used to compare the groups, in addition to Spearman's correlation. Results: Eighty-five individuals with diabetes mellitus 2 (20%; n=17) and without diabetes mellitus (80%; n=68) participated, 34% (n=29) were adults and 66% (n=56) were elderly. Adults and elderly people with diabetes mellitus presented hyperglycemia in relation to non-diabetic patients (p<0.01). Higher values of glycemic standard deviation (p<0.01) and glycemic variation coefficient in relation to patients without diabetes (p= 0.03), however, were not classified with glycemic variability. The C-reactive protein values were correlated with the glycemic standard deviation (R= 0.29; p= 0.0065), however, the amount of carbohydrates infused in the enteral diet was not statistically correlated with glycemia or with the glycemic variability of patients (p>0.05). Conclusion: hospitalized patients with or without diabetes mellitus 2 did not show glycemic variability, demonstrating glycemic control during hospitalization.
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Copyright (c) 2022 Daiana Friedrich Marquetto, Cristina Dalmolin, Mairin Schott, Anieli Golin, Danielly Oberoffer Stefenon, Juliana Ebling Brondani, Milena Cervo Cassol, Elisângela Colpo
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